Magnesium in PDB 9dw5: Dephosphorylated Cftr in 1:1 Complex with Pka-C (Site I)

All present enzymatic activity of Dephosphorylated Cftr in 1:1 Complex with Pka-C (Site I):
2.7.11.11; 5.6.1.6;

The binding sites of Magnesium atom in the Dephosphorylated Cftr in 1:1 Complex with Pka-C (Site I) (pdb code 9dw5). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Dephosphorylated Cftr in 1:1 Complex with Pka-C (Site I), PDB code: 9dw5:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Dephosphorylated Cftr in 1:1 Complex with Pka-C (Site I)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Dephosphorylated Cftr in 1:1 Complex with Pka-C (Site I) within 5.0Å range: probe atom residue distance (Å) B Occ G:Mg401 b:231.5 occ:1.00 O1B G:ANP403 2.0 202.5 1.0 O3G G:ANP403 2.0 202.5 1.0 N3B G:ANP403 2.1 202.5 1.0 N G:SER54 2.2 238.8 1.0 PG G:ANP403 2.3 202.5 1.0 CA G:GLY53 2.4 237.3 1.0 PB G:ANP403 2.4 202.5 1.0 C G:GLY53 2.5 237.3 1.0 O1G G:ANP403 3.1 202.5 1.0 O3A G:ANP403 3.3 202.5 1.0 CA G:SER54 3.3 238.8 1.0 O2B G:ANP403 3.6 202.5 1.0 O2G G:ANP403 3.6 202.5 1.0 O G:GLY53 3.7 237.3 1.0 CB G:SER54 3.7 238.8 1.0 O2A G:ANP403 3.7 202.5 1.0 N G:GLY53 3.8 237.3 1.0 MG G:MG402 3.9 174.7 1.0 PA G:ANP403 4.1 202.5 1.0 O G:THR52 4.5 229.7 1.0 C G:THR52 4.6 229.7 1.0 C G:SER54 4.6 238.8 1.0 C5' G:ANP403 4.7 202.5 1.0 O5' G:ANP403 5.0 202.5 1.0 N G:PHE55 5.0 235.9 1.0

Magnesium binding site 2 out of 2 in the Dephosphorylated Cftr in 1:1 Complex with Pka-C (Site I)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Dephosphorylated Cftr in 1:1 Complex with Pka-C (Site I) within 5.0Å range: probe atom residue distance (Å) B Occ G:Mg402 b:174.7 occ:1.00 O2G G:ANP403 2.1 202.5 1.0 N3B G:ANP403 2.1 202.5 1.0 OD1 G:ASN172 2.1 121.0 1.0 PG G:ANP403 2.4 202.5 1.0 O2A G:ANP403 3.0 202.5 1.0 CG G:ASN172 3.2 121.0 1.0 CB G:ASP185 3.3 130.1 1.0 O1G G:ANP403 3.4 202.5 1.0 O3G G:ANP403 3.6 202.5 1.0 PB G:ANP403 3.6 202.5 1.0 ND2 G:ASN172 3.8 121.0 1.0 MG G:MG401 3.9 231.5 1.0 O2B G:ANP403 4.0 202.5 1.0 PA G:ANP403 4.1 202.5 1.0 CB G:ASN172 4.3 121.0 1.0 O1A G:ANP403 4.3 202.5 1.0 O3A G:ANP403 4.3 202.5 1.0 CA G:ASP185 4.7 130.1 1.0 O1B G:ANP403 4.7 202.5 1.0 CA G:ASN172 4.7 121.0 1.0

K.Fiedorczuk, I.Iordanov, C.Mihalyi, A.Szollosi, L.Csanady, J.Chen. The Structures of Protein Kinase A in Complex with Cftr: Mechanisms of Phosphorylation and Non-Catalytic Activation To Be Published.