Magnesium in PDB 9dw7: Dephosphorylated Cftr in 1:2 Complex with Pka-C

All present enzymatic activity of Dephosphorylated Cftr in 1:2 Complex with Pka-C:
2.7.11.11; 5.6.1.6;

The binding sites of Magnesium atom in the Dephosphorylated Cftr in 1:2 Complex with Pka-C (pdb code 9dw7). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Dephosphorylated Cftr in 1:2 Complex with Pka-C, PDB code: 9dw7:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Dephosphorylated Cftr in 1:2 Complex with Pka-C


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Dephosphorylated Cftr in 1:2 Complex with Pka-C within 5.0Å range: probe atom residue distance (Å) B Occ G:Mg401 b:13.4 occ:1.00 O2B G:ANP403 1.9 2.6 1.0 N3B G:ANP403 2.0 2.8 1.0 N G:SER54 2.2 262.9 1.0 PB G:ANP403 2.2 2.7 1.0 O3G G:ANP403 2.2 9.6 1.0 PG G:ANP403 2.4 0.6 1.0 C G:GLY53 2.8 233.4 1.0 CA G:GLY53 2.9 236.2 1.0 CA G:SER54 3.1 268.2 1.0 O1G G:ANP403 3.1 5.4 1.0 O3A G:ANP403 3.2 5.2 1.0 CB G:SER54 3.4 265.4 1.0 O1B G:ANP403 3.5 4.1 1.0 O2G G:ANP403 3.7 2.4 1.0 O G:GLY53 3.9 240.8 1.0 MG G:MG402 4.0 5.6 1.0 O2A G:ANP403 4.0 5.0 1.0 N G:GLY53 4.1 239.9 1.0 PA G:ANP403 4.2 8.8 1.0 C G:SER54 4.5 263.6 1.0

Magnesium binding site 2 out of 2 in the Dephosphorylated Cftr in 1:2 Complex with Pka-C


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Dephosphorylated Cftr in 1:2 Complex with Pka-C within 5.0Å range: probe atom residue distance (Å) B Occ G:Mg402 b:5.6 occ:1.00 O2G G:ANP403 1.9 2.4 1.0 N3B G:ANP403 2.1 2.8 1.0 PG G:ANP403 2.3 0.6 1.0 O2A G:ANP403 2.9 5.0 1.0 O1G G:ANP403 3.0 5.4 1.0 O G:GLU171 3.3 6.3 1.0 PB G:ANP403 3.4 2.7 1.0 O1B G:ANP403 3.5 4.1 1.0 O3G G:ANP403 3.6 9.6 1.0 MG G:MG401 4.0 13.4 1.0 PA G:ANP403 4.1 8.8 1.0 CB G:ASP185 4.1 80.0 1.0 O3A G:ANP403 4.2 5.2 1.0 C G:GLU171 4.3 0.7 1.0 O1A G:ANP403 4.4 1.7 1.0 O2B G:ANP403 4.5 2.6 1.0 CB G:GLU171 4.7 0.4 1.0 CA G:ASN172 4.8 17.1 1.0 N G:ASN172 4.9 12.1 1.0

K.Fiedorczuk, I.Iordanov, C.Mihalyi, A.Szollosi, L.Csanady, J.Chen. The Structures of Protein Kinase A in Complex with Cftr: Mechanisms of Phosphorylation and Non-Catalytic Activation To Be Published.