Magnesium in PDB 9enb: Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln

All present enzymatic activity of Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln:
5.4.99.45;

The binding sites of Magnesium atom in the Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln (pdb code 9enb). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 6 binding sites of Magnesium where determined in the Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln, PDB code: 9enb:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6;

Magnesium binding site 1 out of 6 in the Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg101 b:94.1 occ:1.00 OP2 C:G10 2.8 95.2 1.0 OP1 C:G9 3.3 89.2 1.0 O5' C:G9 3.4 89.2 1.0 P C:G9 4.1 89.2 1.0 P C:G10 4.1 95.2 1.0 OP1 C:G10 4.6 95.2 1.0 C5' C:G9 4.6 89.2 1.0 C4' C:G9 4.6 89.2 1.0 O2' C:A46 4.8 90.3 1.0 O3' C:U8 4.8 96.2 1.0 O3' C:G9 4.9 89.2 1.0 OP2 C:U11 5.0 97.8 1.0

Magnesium binding site 2 out of 6 in the Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg102 b:86.0 occ:1.00 OP2 C:G9 2.2 89.2 1.0 OP1 C:U8 2.6 96.2 1.0 P C:G9 3.2 89.2 1.0 OP1 C:G9 3.5 89.2 1.0 OP2 C:G12 3.7 98.2 1.0 P C:U8 3.7 96.2 1.0 O5' C:G9 4.2 89.2 1.0 OP2 C:U8 4.2 96.2 1.0 O5' C:U8 4.3 96.2 1.0 OP2 C:U11 4.4 97.8 1.0 O3' C:U8 4.4 96.2 1.0 C5' C:U8 4.6 96.2 1.0 C3' C:U8 4.6 96.2 1.0 C5' C:G9 4.8 89.2 1.0

Magnesium binding site 3 out of 6 in the Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg103 b:73.6 occ:1.00 OP1 C:A58 2.5 90.0 1.0 O4 C:U59 2.9 90.5 1.0 C4 C:U59 4.0 90.5 1.0 P C:A58 4.0 90.0 1.0 C5 C:U59 4.5 90.5 1.0 O4 C:U47 4.7 95.4 1.0 O5' C:A58 4.7 90.0 1.0 C4' C:A57 4.8 93.2 1.0 N7 C:A58 4.8 90.0 1.0 O3' C:A57 4.8 93.2 1.0 C8 C:A58 4.9 90.0 1.0 OP2 C:A58 4.9 90.0 1.0

Magnesium binding site 4 out of 6 in the Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg101 b:74.3 occ:1.00 OP1 D:A58 2.5 89.4 1.0 O4 D:U59 2.9 89.3 1.0 C4 D:U59 4.0 89.3 1.0 P D:A58 4.0 89.4 1.0 C5 D:U59 4.5 89.3 1.0 O4 D:U47 4.7 94.7 1.0 O5' D:A58 4.7 89.4 1.0 C4' D:A57 4.8 92.1 1.0 N7 D:A58 4.8 89.4 1.0 O3' D:A57 4.8 92.1 1.0 C8 D:A58 4.9 89.4 1.0 OP2 D:A58 4.9 89.4 1.0

Magnesium binding site 5 out of 6 in the Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg102 b:82.1 occ:1.00 OP2 D:G9 2.1 88.2 1.0 OP1 D:U8 2.6 96.2 1.0 P D:G9 3.2 88.2 1.0 OP1 D:G9 3.5 88.2 1.0 OP2 D:G12 3.7 97.8 1.0 P D:U8 3.7 96.2 1.0 O5' D:G9 4.2 88.2 1.0 OP2 D:U8 4.2 96.2 1.0 O5' D:U8 4.3 96.2 1.0 O3' D:U8 4.4 96.2 1.0 OP2 D:U11 4.4 97.1 1.0 C5' D:U8 4.6 96.2 1.0 C3' D:U8 4.6 96.2 1.0 C5' D:G9 4.8 88.2 1.0

Magnesium binding site 6 out of 6 in the Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Human Pseudouridine Synthase 3 (PUS3 R116A Mutant) and Two Trna-Gln within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg103 b:89.5 occ:1.00 OP2 D:G10 2.8 94.2 1.0 OP1 D:G9 3.3 88.2 1.0 O5' D:G9 3.4 88.2 1.0 P D:G9 4.0 88.2 1.0 P D:G10 4.1 94.2 1.0 OP1 D:G10 4.6 94.2 1.0 C5' D:G9 4.6 88.2 1.0 C4' D:G9 4.6 88.2 1.0 O2' D:A46 4.8 89.4 1.0 O3' D:U8 4.8 96.2 1.0 O3' D:G9 4.9 88.2 1.0 OP2 D:U11 5.0 97.1 1.0

T.-Y.Lin, L.Koziej, S.Glatt. The Molecular Basis of Trna Selectivity By Human Pseudouridine Synthase 3 (PUS3) Mol.Cell.
ISSN: ISSN 1097-2765
DOI: 10.1016/J.MOLCEL.2024.06.013