Magnesium in PDB 9ere: SLFN11 Dimer Bound to Trna-Leu-Taa

The structure of SLFN11 Dimer Bound to Trna-Leu-Taa also contains other interesting chemical elements:

Zinc	(Zn)	2 atoms
Manganese	(Mn)	3 atoms

The binding sites of Magnesium atom in the SLFN11 Dimer Bound to Trna-Leu-Taa (pdb code 9ere). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the SLFN11 Dimer Bound to Trna-Leu-Taa, PDB code: 9ere:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the SLFN11 Dimer Bound to Trna-Leu-Taa


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of SLFN11 Dimer Bound to Trna-Leu-Taa within 5.0Å range: probe atom residue distance (Å) B Occ T:Mg101 b:22.2 occ:1.00 OP1 T:C58 1.9 66.4 1.0 OP2 T:U60 2.5 55.0 1.0 P T:C58 3.4 66.1 1.0 P T:U60 3.7 59.7 1.0 O5' T:U60 4.0 50.4 1.0 C5 T:U60 4.0 49.8 1.0 OP2 T:C58 4.2 62.5 1.0 O3' T:G57 4.2 75.5 1.0 O5' T:C58 4.3 65.1 1.0 C6 T:U60 4.4 48.7 1.0 OP1 T:U60 4.5 53.1 1.0 OP2 T:G61 4.5 49.1 1.0 C5' T:C58 4.7 65.5 1.0 C4 T:U60 4.9 51.5 1.0 O3' T:G59 4.9 58.8 1.0 N7 T:G61 5.0 43.5 1.0

Magnesium binding site 2 out of 4 in the SLFN11 Dimer Bound to Trna-Leu-Taa


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of SLFN11 Dimer Bound to Trna-Leu-Taa within 5.0Å range: probe atom residue distance (Å) B Occ T:Mg102 b:41.4 occ:1.00 N7 T:G15 2.1 80.5 1.0 C8 T:G15 2.9 79.5 1.0 C5 T:G15 3.3 78.2 1.0 OP2 T:G15 3.5 82.2 1.0 O4 T:U8 3.7 80.0 1.0 O6 T:G15 3.9 76.2 1.0 C6 T:G15 4.0 75.7 1.0 C4 T:U8 4.0 79.7 1.0 N9 T:G15 4.2 78.2 1.0 OP2 T:A14 4.2 95.2 1.0 N3 T:U8 4.4 80.5 1.0 C4 T:G15 4.4 77.0 1.0 C8 T:A14 4.7 91.3 1.0 C5 T:U8 4.8 79.4 1.0 O4 T:U16 4.9 73.4 1.0 N7 T:A14 4.9 91.8 1.0 P T:G15 5.0 88.2 1.0

Magnesium binding site 3 out of 4 in the SLFN11 Dimer Bound to Trna-Leu-Taa


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of SLFN11 Dimer Bound to Trna-Leu-Taa within 5.0Å range: probe atom residue distance (Å) B Occ T:Mg103 b:68.5 occ:1.00 N7 T:G13 2.1 98.8 1.0 C8 T:G13 3.0 99.3 1.0 C5 T:G13 3.2 98.9 1.0 O6 T:G13 3.6 97.7 1.0 OP2 T:G9 3.8 91.6 1.0 C6 T:G13 3.8 98.7 1.0 OP2 T:C12 3.8 106.4 1.0 C5 T:U8 4.2 79.4 1.0 N9 T:G13 4.2 100.5 1.0 OP2 T:U8 4.3 81.4 1.0 C4 T:G13 4.4 99.7 1.0 C6 T:U8 4.4 79.4 1.0 OP2 T:G13 4.6 100.4 1.0 C5 T:C12 4.6 107.1 1.0 C6 T:C12 5.0 107.1 1.0 C4 T:U8 5.0 79.7 1.0

Magnesium binding site 4 out of 4 in the SLFN11 Dimer Bound to Trna-Leu-Taa


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of SLFN11 Dimer Bound to Trna-Leu-Taa within 5.0Å range: probe atom residue distance (Å) B Occ T:Mg104 b:49.6 occ:1.00 OP2 T:A69 2.1 55.3 1.0 OP2 T:G57 3.3 75.7 1.0 P T:A69 3.6 54.0 1.0 N7 T:G57 3.7 75.0 1.0 C8 T:G57 4.0 74.5 1.0 O5' T:A69 4.4 56.1 1.0 OP1 T:A69 4.4 54.9 1.0 O3' T:A68 4.5 54.2 1.0 P T:G57 4.5 82.4 1.0 O5' T:G57 4.5 74.8 1.0 OP1 T:A68 4.6 49.8 1.0 C3' T:A68 4.6 47.4 1.0 C5' T:A69 4.6 57.5 1.0 C5 T:G57 4.7 73.5 1.0 OP2 T:C56 4.8 83.8 1.0 OP2 T:C58 4.9 62.5 1.0

M.Kugler, F.J.Metzner, K.P.Hopfner, K.Lammens. Phosphorylation-Mediated Conformational Change Regulates Human SLFN11 Nat Commun 2024.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-024-54833-7