Magnesium in PDB 9gch: Human Mitochondrial Rnase Z with Trna-His-Cca, SDR5C1/TRMT10C Focus

All present enzymatic activity of Human Mitochondrial Rnase Z with Trna-His-Cca, SDR5C1/TRMT10C Focus:
1.1.1.159; 1.1.1.178; 1.1.1.239; 1.1.1.35; 1.1.1.53; 1.1.1.62; 2.1.1.218; 2.1.1.221;

The binding sites of Magnesium atom in the Human Mitochondrial Rnase Z with Trna-His-Cca, SDR5C1/TRMT10C Focus (pdb code 9gch). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human Mitochondrial Rnase Z with Trna-His-Cca, SDR5C1/TRMT10C Focus, PDB code: 9gch:

Magnesium binding site 1 out of 1 in the Human Mitochondrial Rnase Z with Trna-His-Cca, SDR5C1/TRMT10C Focus


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Mitochondrial Rnase Z with Trna-His-Cca, SDR5C1/TRMT10C Focus within 5.0Å range: probe atom residue distance (Å) B Occ T:Mg102 b:29.8 occ:1.00 OP1 T:U11 2.0 23.6 1.0 O F:HOH607 2.7 20.8 1.0 P T:U11 3.2 18.4 1.0 O4' T:A9 3.2 22.2 1.0 NH2 F:ARG379 3.4 23.9 1.0 CG2 F:THR352 3.6 15.7 1.0 O3' T:G10 3.6 18.7 1.0 NE2 F:GLN355 3.7 16.1 1.0 NH1 F:ARG379 3.7 22.2 1.0 O F:HOH604 3.8 30.3 1.0 OP2 T:U11 3.9 20.6 1.0 C4' T:A9 3.9 23.4 1.0 O F:HOH608 4.0 27.3 1.0 CZ F:ARG379 4.0 23.1 1.0 C5' T:A9 4.0 24.1 1.0 CG F:PRO377 4.2 24.1 1.0 NZ F:LYS380 4.3 23.0 1.0 OE1 F:GLN355 4.4 16.3 1.0 C1' T:A9 4.4 21.7 1.0 O5' T:A9 4.5 26.1 1.0 CD F:GLN355 4.5 15.4 1.0 O5' T:U11 4.5 19.7 1.0 CE F:LYS380 4.6 23.4 1.0 N9 T:A9 4.6 24.2 1.0 C8 T:A9 4.8 24.8 1.0 C3' T:G10 4.9 18.4 1.0 C5' T:U11 5.0 21.1 1.0

G.Valentin Gese, B.M.Hallberg. Structural Basis of 3-Trna Maturation By the Human Mitochondrial Rnase Z Complex Embo J. 2024.
ISSN: ESSN 1460-2075
DOI: 10.1038/S44318-024-00297-W