Magnesium in PDB 24rc: Cryo-Em Structure of Human Sodium Pump W931R Mutant in K+-Occluded E2- Pi State

All present enzymatic activity of Cryo-Em Structure of Human Sodium Pump W931R Mutant in K+-Occluded E2- Pi State:
7.2.2.13;

The structure of Cryo-Em Structure of Human Sodium Pump W931R Mutant in K+-Occluded E2- Pi State also contains other interesting chemical elements:

Potassium	(K)	3 atoms
Fluorine	(F)	4 atoms
Aluminium	(Al)	1 atom

The binding sites of Magnesium atom in the Cryo-Em Structure of Human Sodium Pump W931R Mutant in K+-Occluded E2- Pi State (pdb code 24rc). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of Human Sodium Pump W931R Mutant in K+-Occluded E2- Pi State, PDB code: 24rc:

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of Human Sodium Pump W931R Mutant in K+-Occluded E2- Pi State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Human Sodium Pump W931R Mutant in K+-Occluded E2- Pi State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1102 b:22.6 occ:1.00 O A:THR378 2.0 29.0 1.0 OD1 A:ASP717 2.0 29.0 1.0 F1 A:ALF1101 2.1 33.4 1.0 OD2 A:ASP376 2.5 22.9 1.0 CG A:ASP717 3.1 24.3 1.0 F4 A:ALF1101 3.2 37.1 1.0 CG A:ASP376 3.2 26.9 1.0 C A:THR378 3.2 25.6 1.0 OD1 A:ASP376 3.3 30.7 1.0 AL A:ALF1101 3.4 27.3 1.0 OD2 A:ASP717 3.5 27.9 1.0 CA A:THR378 4.1 23.0 1.0 CB A:THR378 4.1 23.8 1.0 N A:GLY379 4.2 25.2 1.0 F3 A:ALF1101 4.2 23.4 1.0 OD2 A:ASP721 4.2 31.6 1.0 N A:THR378 4.3 24.3 1.0 O A:GLY220 4.3 24.0 1.0 N A:GLY718 4.4 21.1 1.0 CB A:ASP717 4.4 21.3 1.0 CA A:GLY379 4.4 23.9 1.0 N A:ASP717 4.4 26.8 1.0 C A:ASP717 4.5 23.4 1.0 OG1 A:THR380 4.6 24.3 1.0 CB A:ASP376 4.6 21.1 1.0 CG2 A:THR378 4.6 23.4 1.0 CA A:ASP717 4.7 22.8 1.0 CA A:GLY220 4.8 22.8 1.0 CA A:GLY718 4.8 21.9 1.0 N A:THR380 4.8 25.4 1.0 C A:GLY379 4.9 25.5 1.0 F2 A:ALF1101 4.9 28.9 1.0

P.Artigas, K.Abe. On the Mechanism of Hypomagnesimia with Treatment-Resistant Seizures Cansed By Variants of the Na+,K+-Atpase ALPHA1 Subunit (ATP1A1) To Be Published.