Magnesium in PDB 6pek: Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide

All present enzymatic activity of Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide:
5.6.1.1;

The structure of Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide also contains other interesting chemical elements:

Fluorine

(F)

12 atoms

The binding sites of Magnesium atom in the Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide (pdb code 6pek). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide, PDB code: 6pek:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg703 b:84.4 occ:1.00 O2B A:ADP701 2.1 84.4 1.0 OG1 A:THR389 2.2 84.7 1.0 F1 A:BEF702 2.2 84.4 1.0 O1B A:ADP701 2.7 84.4 1.0 PB A:ADP701 2.8 84.4 1.0 OD2 A:ASP441 2.9 86.2 1.0 BE A:BEF702 3.3 84.4 1.0 O3B A:ADP701 3.4 84.4 1.0 CB A:THR389 3.4 84.7 1.0 CG A:ASP441 3.7 86.2 1.0 OD1 A:ASP441 3.7 86.2 1.0 NH2 B:ARG499 4.0 73.7 1.0 N A:THR389 4.2 84.7 1.0 O3A A:ADP701 4.2 84.4 1.0 F3 A:BEF702 4.3 84.4 1.0 CA A:THR389 4.4 84.7 1.0 NH2 B:ARG498 4.4 76.5 1.0 F2 A:BEF702 4.4 84.4 1.0 CG2 A:THR389 4.4 84.7 1.0 OD1 B:ASP470 4.4 80.3 1.0 O1A A:ADP701 4.8 84.4 1.0 CB A:LYS388 5.0 81.1 1.0 OD2 B:ASP470 5.0 80.3 1.0

Magnesium binding site 2 out of 4 in the Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg703 b:63.5 occ:1.00 O2B B:ADP701 2.1 63.5 1.0 OG1 B:THR389 2.1 64.2 1.0 F1 B:BEF702 2.2 63.5 1.0 PB B:ADP701 2.9 63.5 1.0 O1B B:ADP701 2.9 63.5 1.0 OD2 B:ASP441 3.0 69.0 1.0 BE B:BEF702 3.4 63.5 1.0 CB B:THR389 3.5 64.2 1.0 O3B B:ADP701 3.5 63.5 1.0 OD1 B:ASP441 3.6 69.0 1.0 CG B:ASP441 3.7 69.0 1.0 N B:THR389 4.0 64.2 1.0 CA B:THR389 4.2 64.2 1.0 F3 B:BEF702 4.3 63.5 1.0 O3A B:ADP701 4.4 63.5 1.0 F2 B:BEF702 4.4 63.5 1.0 CG2 B:THR389 4.5 64.2 1.0 OD2 C:ASP470 4.8 65.2 1.0 NH2 C:ARG498 4.8 64.0 1.0 NH2 C:ARG499 4.9 61.6 1.0 CB B:LYS388 4.9 63.5 1.0 OD1 C:ASP470 4.9 65.2 1.0

Magnesium binding site 3 out of 4 in the Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg703 b:57.4 occ:1.00 O2B C:ADP701 2.1 57.4 1.0 OG1 C:THR389 2.2 54.6 1.0 F1 C:BEF702 2.2 57.4 1.0 PB C:ADP701 2.9 57.4 1.0 O1B C:ADP701 2.9 57.4 1.0 OD2 C:ASP441 3.0 60.9 1.0 OD1 C:ASP441 3.2 60.9 1.0 BE C:BEF702 3.3 57.4 1.0 O3B C:ADP701 3.4 57.4 1.0 CB C:THR389 3.5 54.6 1.0 CG C:ASP441 3.5 60.9 1.0 N C:THR389 3.9 54.6 1.0 CA C:THR389 4.1 54.6 1.0 F3 C:BEF702 4.3 57.4 1.0 O3A C:ADP701 4.4 57.4 1.0 F2 C:BEF702 4.4 57.4 1.0 CG2 C:THR389 4.5 54.6 1.0 NH2 D:ARG499 4.6 60.6 1.0 CB C:LYS388 4.6 53.6 1.0 C C:LYS388 4.9 53.6 1.0 NH2 D:ARG498 4.9 60.5 1.0 CB C:ALA485 4.9 55.7 1.0 CB C:ASP441 5.0 60.9 1.0

Magnesium binding site 4 out of 4 in the Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Structure of Spastin Hexamer (Subunit A-E) in Complex with Substrate Peptide within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg703 b:78.4 occ:1.00 OG1 D:THR389 1.9 80.3 1.0 O2B D:ADP701 2.0 78.4 1.0 F1 D:BEF702 2.0 78.4 1.0 O1B D:ADP701 2.4 78.4 1.0 PB D:ADP701 2.7 78.4 1.0 BE D:BEF702 3.2 78.4 1.0 CB D:THR389 3.2 80.3 1.0 O3B D:ADP701 3.4 78.4 1.0 OD2 D:ASP441 3.7 75.2 1.0 F3 D:BEF702 3.8 78.4 1.0 N D:THR389 3.8 80.3 1.0 CA D:THR389 4.1 80.3 1.0 OD1 D:ASP441 4.1 75.2 1.0 O3A D:ADP701 4.1 78.4 1.0 CG2 D:THR389 4.2 80.3 1.0 CG D:ASP441 4.3 75.2 1.0 F2 D:BEF702 4.5 78.4 1.0 NH2 E:ARG499 4.6 98.5 1.0 O1A D:ADP701 4.6 78.4 1.0 O2A D:ADP701 4.6 78.4 1.0 PA D:ADP701 4.7 78.4 1.0 CB D:LYS388 4.8 73.6 1.0 C D:LYS388 4.9 73.6 1.0

H.Han, H.L.Schubert, J.Mccullough, N.Monroe, W.I.Sundquist, C.P.Hill. Structure of the Microtubule Severing Protein Spastin Bound to A Glutamte-Rich Peptide Implies A Hand-Over-Hand Mechanism of Substrate Translocation. To Be Published.