Magnesium in PDB 159d: Side By Side Binding of Two Distamycin A Drugs in the Minor Groove of An Alternating B-Dna Duplex

The structure of Side By Side Binding of Two Distamycin A Drugs in the Minor Groove of An Alternating B-Dna Duplex, PDB code: 159d was solved by X.Chen, B.Ramakrishnan, S.T.Rao, M.Sundaralingam, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 1.80
Space group	P 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	27.930, 27.930, 57.670, 90.00, 90.00, 90.00
R / Rfree (%)	15 / n/a

The binding sites of Magnesium atom in the Side By Side Binding of Two Distamycin A Drugs in the Minor Groove of An Alternating B-Dna Duplex (pdb code 159d). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Side By Side Binding of Two Distamycin A Drugs in the Minor Groove of An Alternating B-Dna Duplex, PDB code: 159d:

Magnesium binding site 1 out of 1 in the Side By Side Binding of Two Distamycin A Drugs in the Minor Groove of An Alternating B-Dna Duplex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Side By Side Binding of Two Distamycin A Drugs in the Minor Groove of An Alternating B-Dna Duplex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg10 b:9.2 occ:1.00 OP2 A:DC6 1.9 9.6 1.0 O A:HOH19 2.0 8.8 1.0 O A:HOH11 2.0 8.0 1.0 O A:HOH20 2.1 10.9 1.0 P A:DC6 3.4 9.5 1.0 O A:HOH44 3.9 65.5 1.0 O5' A:DC6 4.0 9.4 1.0 C3' A:DI5 4.1 9.4 1.0 O3' A:DI5 4.3 9.3 1.0 C2' A:DI5 4.3 9.2 1.0 O A:HOH24 4.3 22.5 1.0 O A:HOH51 4.3 33.6 1.0 OP1 A:DC6 4.5 9.6 1.0 O A:HOH15 4.7 14.0 1.0

X.Chen, B.Ramakrishnan, S.T.Rao, M.Sundaralingam. Binding of Two Distamycin A Molecules in the Minor Groove of An Alternating B-Dna Duplex. Nat.Struct.Biol. V. 1 169 1994.
ISSN: ISSN 1072-8368
PubMed: 7656035
DOI: 10.1038/NSB0394-169