Magnesium in PDB 1b39: Human Cyclin-Dependent Kinase 2 Phosphorylated on Thr 160

All present enzymatic activity of Human Cyclin-Dependent Kinase 2 Phosphorylated on Thr 160:
2.7.1.37;

The structure of Human Cyclin-Dependent Kinase 2 Phosphorylated on Thr 160, PDB code: 1b39 was solved by N.R.Brown, M.E.M.Noble, A.M.Lawrie, M.C.Morris, P.Tunnah, G.Divita, L.N.Johnson, J.A.Endicott, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	53.420, 71.660, 72.520, 90.00, 90.00, 90.00
R / Rfree (%)	20 / 27

The binding sites of Magnesium atom in the Human Cyclin-Dependent Kinase 2 Phosphorylated on Thr 160 (pdb code 1b39). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human Cyclin-Dependent Kinase 2 Phosphorylated on Thr 160, PDB code: 1b39:

Magnesium binding site 1 out of 1 in the Human Cyclin-Dependent Kinase 2 Phosphorylated on Thr 160


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Cyclin-Dependent Kinase 2 Phosphorylated on Thr 160 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg382 b:36.3 occ:0.60 OD1 A:ASN132 2.0 34.3 1.0 OD2 A:ASP145 2.1 34.3 1.0 O2G A:ATP381 2.1 50.3 1.0 O A:HOH527 2.2 31.6 1.0 O1B A:ATP381 2.2 44.6 1.0 O2A A:ATP381 2.4 44.4 1.0 PB A:ATP381 3.2 45.1 1.0 CG A:ASN132 3.2 34.1 1.0 PA A:ATP381 3.2 46.9 1.0 CG A:ASP145 3.3 34.1 1.0 O3A A:ATP381 3.4 46.0 1.0 PG A:ATP381 3.4 49.0 1.0 O3B A:ATP381 3.7 46.9 1.0 O5' A:ATP381 3.7 45.4 1.0 ND2 A:ASN132 3.7 32.6 1.0 NZ A:LYS33 4.0 38.2 1.0 CB A:ASP145 4.1 29.1 1.0 O3G A:ATP381 4.2 51.6 1.0 OD1 A:ASP145 4.2 34.6 1.0 CB A:ASN132 4.4 27.6 1.0 O1G A:ATP381 4.4 49.0 1.0 O2B A:ATP381 4.5 44.9 1.0 O A:GLN131 4.6 24.8 1.0 CA A:ASN132 4.6 22.5 1.0 O1A A:ATP381 4.6 45.2 1.0 C2' A:ATP381 4.9 49.0 1.0 N A:ASN132 5.0 21.8 1.0

N.R.Brown, M.E.Noble, A.M.Lawrie, M.C.Morris, P.Tunnah, G.Divita, L.N.Johnson, J.A.Endicott. Effects of Phosphorylation of Threonine 160 on Cyclin-Dependent Kinase 2 Structure and Activity. J.Biol.Chem. V. 274 8746 1999.
ISSN: ISSN 0021-9258
PubMed: 10085115
DOI: 10.1074/JBC.274.13.8746