Magnesium in PDB 1dtw: Human Branched-Chain Alpha-Keto Acid Dehydrogenase

All present enzymatic activity of Human Branched-Chain Alpha-Keto Acid Dehydrogenase:
1.2.4.4;

The structure of Human Branched-Chain Alpha-Keto Acid Dehydrogenase, PDB code: 1dtw was solved by A.Aevarsson, J.L.Chuang, R.M.Wynn, S.Turley, D.T.Chuang, W.G.J.Hol, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.70
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	143.760, 143.760, 69.160, 90.00, 90.00, 120.00
R / Rfree (%)	22.4 / 27.9

The structure of Human Branched-Chain Alpha-Keto Acid Dehydrogenase also contains other interesting chemical elements:

Potassium

(K)

2 atoms

The binding sites of Magnesium atom in the Human Branched-Chain Alpha-Keto Acid Dehydrogenase (pdb code 1dtw). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human Branched-Chain Alpha-Keto Acid Dehydrogenase, PDB code: 1dtw:

Magnesium binding site 1 out of 1 in the Human Branched-Chain Alpha-Keto Acid Dehydrogenase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Branched-Chain Alpha-Keto Acid Dehydrogenase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg401 b:28.3 occ:1.00 O A:TYR224 2.1 35.0 1.0 OD1 A:ASN222 2.1 34.1 1.0 O12 A:TDP403 2.1 40.2 1.0 O A:HOH417 2.2 16.8 1.0 O23 A:TDP403 2.4 40.1 1.0 OE1 A:GLU193 2.5 27.6 1.0 CG A:ASN222 3.0 34.0 1.0 CD A:GLU193 3.2 27.6 1.0 P1 A:TDP403 3.2 40.3 1.0 OE2 A:GLU193 3.2 27.6 1.0 P2 A:TDP403 3.3 40.2 1.0 O11 A:TDP403 3.3 40.2 1.0 ND2 A:ASN222 3.3 34.0 1.0 C A:TYR224 3.3 35.0 1.0 O21 A:TDP403 3.5 40.0 1.0 O A:ARG220 4.1 32.9 1.0 N A:TYR224 4.2 34.8 1.0 N A:GLU193 4.2 27.4 1.0 N A:ALA225 4.2 35.0 1.0 N A:ASN222 4.3 33.7 1.0 O13 A:TDP403 4.3 40.2 1.0 CA A:TYR224 4.3 34.9 1.0 CB A:ASN222 4.3 34.0 1.0 O5G A:TDP403 4.3 40.2 1.0 CA A:ALA225 4.4 35.1 1.0 CA A:GLY192 4.5 27.6 1.0 N A:GLY194 4.6 27.0 1.0 O22 A:TDP403 4.6 40.1 1.0 CG A:GLU193 4.6 27.4 1.0 CA A:ASN222 4.7 33.9 1.0 C A:GLY192 4.8 27.5 1.0 C A:ASN222 4.8 34.1 1.0 NH1 A:ARG220 5.0 33.0 1.0 CB A:ALA225 5.0 35.1 1.0

A.Aevarsson, J.L.Chuang, R.M.Wynn, S.Turley, D.T.Chuang, W.G.Hol. Crystal Structure of Human Branched-Chain Alpha-Ketoacid Dehydrogenase and the Molecular Basis of Multienzyme Complex Deficiency in Maple Syrup Urine Disease. Structure Fold.Des. V. 8 277 2000.
ISSN: ISSN 0969-2126
PubMed: 10745006
DOI: 10.1016/S0969-2126(00)00105-2