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Atomistry » Magnesium » PDB 1duh-1e9a » 1e99 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 1duh-1e9a » 1e99 » |
Magnesium in PDB 1e99: Human Thymidylate Kinase Complexed with Aztmp and AdpEnzymatic activity of Human Thymidylate Kinase Complexed with Aztmp and Adp
All present enzymatic activity of Human Thymidylate Kinase Complexed with Aztmp and Adp:
2.7.4.9; Protein crystallography data
The structure of Human Thymidylate Kinase Complexed with Aztmp and Adp, PDB code: 1e99
was solved by
N.Ostermann,
A.Lavie,
S.Padiyar,
R.Brundiers,
T.Veit,
J.Reinstein,
R.S.Goody,
M.Konrad,
I.Schlichting,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Human Thymidylate Kinase Complexed with Aztmp and Adp
(pdb code 1e99). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Human Thymidylate Kinase Complexed with Aztmp and Adp, PDB code: 1e99: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 1e99Go back to Magnesium Binding Sites List in 1e99
Magnesium binding site 1 out
of 2 in the Human Thymidylate Kinase Complexed with Aztmp and Adp
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 1e99Go back to Magnesium Binding Sites List in 1e99
Magnesium binding site 2 out
of 2 in the Human Thymidylate Kinase Complexed with Aztmp and Adp
Mono view Stereo pair view
Reference:
N.Ostermann,
A.Lavie,
S.Padiyar,
R.Brundiers,
T.Veit,
J.Reintein,
R.S.Goody,
M.Konrad,
I.Schlichting.
Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons For the Mutants' Improved Kinetics with the Hiv Prodrug Metabolite Aztmp J.Mol.Biol. V. 304 43 2000.
Page generated: Tue Aug 13 02:52:32 2024
ISSN: ISSN 0022-2836 PubMed: 11071809 DOI: 10.1006/JMBI.2000.4175 |
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