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Atomistry » Magnesium » PDB 1e9b-1enn » 1e9f » |
Magnesium in PDB 1e9f: Mutant Human Thymidylate Kinase Complexed with Tmp and AdpEnzymatic activity of Mutant Human Thymidylate Kinase Complexed with Tmp and Adp
All present enzymatic activity of Mutant Human Thymidylate Kinase Complexed with Tmp and Adp:
2.7.4.9; Protein crystallography data
The structure of Mutant Human Thymidylate Kinase Complexed with Tmp and Adp, PDB code: 1e9f
was solved by
N.Ostermann,
A.Lavie,
S.Padiyar,
R.Brundiers,
T.Veit,
J.Reinstein,
R.S.Goody,
M.Konrad,
I.Schlichting,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Mutant Human Thymidylate Kinase Complexed with Tmp and Adp
(pdb code 1e9f). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Mutant Human Thymidylate Kinase Complexed with Tmp and Adp, PDB code: 1e9f: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 1e9fGo back to Magnesium Binding Sites List in 1e9f
Magnesium binding site 1 out
of 2 in the Mutant Human Thymidylate Kinase Complexed with Tmp and Adp
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 1e9fGo back to Magnesium Binding Sites List in 1e9f
Magnesium binding site 2 out
of 2 in the Mutant Human Thymidylate Kinase Complexed with Tmp and Adp
Mono view Stereo pair view
Reference:
N.Ostermann,
A.Lavie,
S.Padiyar,
R.Brundiers,
T.Veit,
J.Reintein,
R.S.Goody,
M.Konrad,
I.Schlichting.
Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons For the Mutants' Improved Kinetics with the Hiv Prodrug Metabolite Aztmp J.Mol.Biol. V. 304 43 2000.
Page generated: Mon Dec 14 05:51:39 2020
ISSN: ISSN 0022-2836 PubMed: 11071809 DOI: 10.1006/JMBI.2000.4175 |
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