Magnesium in PDB 1f5n: Human Guanylate Binding Protein-1 in Complex with the Gtp Analogue, Gmppnp.

The structure of Human Guanylate Binding Protein-1 in Complex with the Gtp Analogue, Gmppnp., PDB code: 1f5n was solved by B.Prakash, L.Renault, G.J.K.Praefcke, C.Herrmann, A.Wittinghofer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.19 / 1.70
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	161.228, 42.652, 91.544, 90.00, 100.19, 90.00
R / Rfree (%)	22.6 / 25.5

The binding sites of Magnesium atom in the Human Guanylate Binding Protein-1 in Complex with the Gtp Analogue, Gmppnp. (pdb code 1f5n). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human Guanylate Binding Protein-1 in Complex with the Gtp Analogue, Gmppnp., PDB code: 1f5n:

Magnesium binding site 1 out of 1 in the Human Guanylate Binding Protein-1 in Complex with the Gtp Analogue, Gmppnp.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Guanylate Binding Protein-1 in Complex with the Gtp Analogue, Gmppnp. within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg595 b:12.4 occ:1.00 O A:HOH999 2.2 11.7 1.0 OG1 A:THR75 2.2 10.1 1.0 OG A:SER52 2.2 10.1 1.0 O2G A:GNP593 2.2 9.2 1.0 O2B A:GNP593 2.2 9.6 1.0 O A:HOH606 2.3 11.2 1.0 CB A:THR75 3.1 12.1 1.0 CB A:SER52 3.2 11.7 1.0 PG A:GNP593 3.2 11.9 1.0 PB A:GNP593 3.3 10.7 1.0 N3B A:GNP593 3.5 9.3 1.0 O3G A:GNP593 3.8 13.3 1.0 OD2 A:ASP97 3.8 15.6 1.0 N A:THR75 3.9 13.5 1.0 N A:SER52 4.0 9.7 1.0 O2A A:GNP593 4.0 12.3 1.0 O A:HOH684 4.1 21.5 1.0 CA A:THR75 4.1 12.5 1.0 CA A:SER52 4.2 9.7 1.0 CG2 A:THR75 4.2 13.1 1.0 OD1 A:ASP97 4.2 15.3 1.0 O3A A:GNP593 4.3 10.8 1.0 O1B A:GNP593 4.4 9.9 1.0 O A:SER66 4.4 14.5 1.0 CG A:ASP97 4.4 13.6 1.0 O1G A:GNP593 4.5 12.2 1.0 PA A:GNP593 4.5 12.4 1.0 O A:THR98 4.6 14.0 1.0 O1A A:GNP593 4.7 11.6 1.0 CB A:HIS74 4.8 17.1 1.0 CB A:LYS51 5.0 8.2 1.0 NZ A:LYS51 5.0 9.3 1.0

B.Prakash, L.Renault, G.J.Praefcke, C.Herrmann, A.Wittinghofer. Triphosphate Structure of Guanylate-Binding Protein 1 and Implications For Nucleotide Binding and Gtpase Mechanism. Embo J. V. 19 4555 2000.
ISSN: ISSN 0261-4189
PubMed: 10970849
DOI: 10.1093/EMBOJ/19.17.4555