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Magnesium in PDB 1ghz: A Novel Serine Protease Inhibition Motif Involving A Multi-Centered Short Hydrogen Bonding Network at the Active Site

Enzymatic activity of A Novel Serine Protease Inhibition Motif Involving A Multi-Centered Short Hydrogen Bonding Network at the Active Site

All present enzymatic activity of A Novel Serine Protease Inhibition Motif Involving A Multi-Centered Short Hydrogen Bonding Network at the Active Site:
3.4.21.4;

Protein crystallography data

The structure of A Novel Serine Protease Inhibition Motif Involving A Multi-Centered Short Hydrogen Bonding Network at the Active Site, PDB code: 1ghz was solved by B.A.Katz, K.Elrod, C.Luong, M.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hatayte, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 7.50 / 1.39
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 54.910, 54.910, 109.420, 90.00, 90.00, 120.00
R / Rfree (%) 17.5 / 21.2

Other elements in 1ghz:

The structure of A Novel Serine Protease Inhibition Motif Involving A Multi-Centered Short Hydrogen Bonding Network at the Active Site also contains other interesting chemical elements:

Calcium (Ca) 1 atom

Magnesium Binding Sites:

The binding sites of Magnesium atom in the A Novel Serine Protease Inhibition Motif Involving A Multi-Centered Short Hydrogen Bonding Network at the Active Site (pdb code 1ghz). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the A Novel Serine Protease Inhibition Motif Involving A Multi-Centered Short Hydrogen Bonding Network at the Active Site, PDB code: 1ghz:

Magnesium binding site 1 out of 1 in 1ghz

Go back to Magnesium Binding Sites List in 1ghz
Magnesium binding site 1 out of 1 in the A Novel Serine Protease Inhibition Motif Involving A Multi-Centered Short Hydrogen Bonding Network at the Active Site


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of A Novel Serine Protease Inhibition Motif Involving A Multi-Centered Short Hydrogen Bonding Network at the Active Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg263

b:17.6
occ:1.00
HA3 A:GLY197 2.3 10.7 1.0
H2 A:HOH250 2.5 11.5 1.0
HA3 A:GLY43 2.7 6.9 1.0
HA3 A:GLY140 2.7 11.2 1.0
O A:SER139 2.7 10.3 1.0
HA2 A:GLY140 2.9 12.2 1.0
O A:ASP194 2.9 9.2 1.0
HA A:ASP194 3.0 11.5 1.0
O A:HOH250 3.0 13.2 1.0
OE1 A:GLN30 3.2 16.0 1.0
CA A:GLY197 3.2 9.9 1.0
CA A:GLY140 3.3 11.4 1.0
H1 A:HOH250 3.4 13.0 1.0
HD2 A:PRO198 3.4 8.8 1.0
H A:GLY197 3.5 9.1 1.0
HE21 A:GLN30 3.5 11.0 1.0
HA2 A:GLY197 3.5 10.3 1.0
C A:ASP194 3.7 11.2 1.0
HB3 A:ASP194 3.7 11.4 1.0
N A:GLY197 3.7 9.3 1.0
C A:SER139 3.7 10.4 1.0
CA A:ASP194 3.7 12.4 1.0
CA A:GLY43 3.8 7.8 1.0
H A:TRP141 4.0 9.7 1.0
N A:GLY140 4.0 10.5 1.0
CD A:GLN30 4.1 11.5 1.0
NE2 A:GLN30 4.1 10.0 1.0
HG23 A:VAL213 4.1 8.8 1.0
H A:GLY43 4.2 9.0 1.0
CB A:ASP194 4.2 11.0 1.0
HA2 A:GLY43 4.3 8.4 1.0
CD A:PRO198 4.3 10.5 1.0
HD3 A:PRO198 4.3 9.0 1.0
N A:GLY43 4.3 9.0 1.0
C A:GLY197 4.4 10.4 1.0
OD2 A:ASP194 4.4 13.5 1.0
C A:GLY140 4.5 12.6 1.0
H A:GLY44 4.6 8.6 1.0
N A:TRP141 4.6 10.1 1.0
O A:GLY193 4.7 13.8 1.0
C A:GLY43 4.7 7.3 1.0
N A:PRO198 4.7 9.7 1.0
O A:SER195 4.7 10.1 1.0
HE3 A:TRP141 4.8 9.8 1.0
CG A:ASP194 4.8 13.3 1.0
C A:GLY196 4.9 7.3 1.0
N A:SER195 4.9 12.3 1.0
HG21 A:VAL213 4.9 9.1 1.0
HE1 A:HIS40 5.0 10.8 1.0
N A:GLY44 5.0 9.1 1.0
H A:GLY140 5.0 10.3 1.0
CG2 A:VAL213 5.0 8.1 1.0
HD13 A:LEU155 5.0 10.0 1.0
HB A:VAL213 5.0 9.9 1.0

Reference:

B.A.Katz, K.Elrod, C.Luong, M.J.Rice, R.L.Mackman, P.A.Sprengeler, J.Spencer, J.Hataye, J.Janc, J.Link, J.Litvak, R.Rai, K.Rice, S.Sideris, E.Verner, W.Young. A Novel Serine Protease Inhibition Motif Involving A Multi-Centered Short Hydrogen Bonding Network at the Active Site. J.Mol.Biol. V. 307 1451 2001.
ISSN: ISSN 0022-2836
PubMed: 11292354
DOI: 10.1006/JMBI.2001.4516
Page generated: Tue Aug 13 03:44:44 2024

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