Magnesium in PDB 1he8: Ras G12V - Pi 3-Kinase Gamma Complex

All present enzymatic activity of Ras G12V - Pi 3-Kinase Gamma Complex:
2.7.1.137;

The structure of Ras G12V - Pi 3-Kinase Gamma Complex, PDB code: 1he8 was solved by M.E.Pacold, S.Suire, O.Perisic, S.Lara-Gonzalez, C.T.Davis, P.T.Hawkins, E.H.Walker, L.Stephens, J.F.Eccleston, R.L.Williams, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	52.03 / 3.00
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	113.635, 113.635, 183.881, 90.00, 90.00, 120.00
R / Rfree (%)	21.2 / 28

The binding sites of Magnesium atom in the Ras G12V - Pi 3-Kinase Gamma Complex (pdb code 1he8). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Ras G12V - Pi 3-Kinase Gamma Complex, PDB code: 1he8:

Magnesium binding site 1 out of 1 in the Ras G12V - Pi 3-Kinase Gamma Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Ras G12V - Pi 3-Kinase Gamma Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg201 b:67.8 occ:1.00 OG B:SER17 2.1 37.0 1.0 O3G B:GNP202 2.4 47.0 1.0 O2B B:GNP202 2.6 43.6 1.0 OG1 B:THR35 2.6 51.9 1.0 CB B:THR35 2.9 50.2 1.0 N3B B:GNP202 3.2 41.0 1.0 PG B:GNP202 3.3 41.7 1.0 CB B:SER17 3.3 36.7 1.0 PB B:GNP202 3.5 41.5 1.0 N B:THR35 3.5 36.9 1.0 CA B:THR35 3.8 36.0 1.0 O B:ASP33 3.9 45.5 1.0 O2A B:GNP202 3.9 46.5 1.0 CG2 B:THR35 4.1 46.1 1.0 O2G B:GNP202 4.1 44.6 1.0 N B:SER17 4.2 25.4 1.0 OD1 B:ASP57 4.3 44.0 1.0 CA B:SER17 4.3 25.6 1.0 O3A B:GNP202 4.4 43.5 1.0 C B:PRO34 4.5 37.8 1.0 O1G B:GNP202 4.5 41.4 1.0 PA B:GNP202 4.5 42.9 1.0 OD2 B:ASP57 4.6 47.4 1.0 O1B B:GNP202 4.6 42.3 1.0 O B:THR58 4.7 36.3 1.0 CG B:ASP57 4.7 46.7 1.0 O1A B:GNP202 4.8 40.5 1.0 CA B:PRO34 4.8 37.3 1.0 O B:HOH301 4.9 25.3 1.0 C B:ASP33 4.9 46.0 1.0 C B:THR35 5.0 35.5 1.0

M.E.Pacold, S.Suire, O.Perisic, S.Lara-Gonzalez, C.T.Davis, E.H.Walker, P.T.Hawkins, L.Stephens, J.F.Eccleston, R.L.Williams. Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase Gamma Cell(Cambridge,Mass.) V. 103 931 2000.
ISSN: ISSN 0092-8674
PubMed: 11136978
DOI: 10.1016/S0092-8674(00)00196-3