Magnesium in PDB 1hnw: Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline

The structure of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline, PDB code: 1hnw was solved by D.E.Brodersen, W.M.Clemons Jr., A.P.Carter, R.Morgan-Warren, B.T.Wimberly, V.Ramakrishnan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.75 / 3.40
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	401.158, 401.158, 176.944, 90.00, 90.00, 90.00
R / Rfree (%)	22.2 / 26.4

The structure of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40; Page 5, Binding sites: 41 - 50; Page 6, Binding sites: 51 - 60; Page 7, Binding sites: 61 - 70; Page 8, Binding sites: 71 - 80; Page 9, Binding sites: 81 - 90; Page 10, Binding sites: 91 - 96;

Binding sites:

The binding sites of Magnesium atom in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline (pdb code 1hnw). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 96 binding sites of Magnesium where determined in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline, PDB code: 1hnw:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Magnesium binding site 1 out of 96 in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1545 b:35.5 occ:0.88 O2 A:C519 2.8 68.3 1.0 O4' A:A520 3.0 60.7 1.0 O2' A:C519 3.5 57.5 1.0 C4' A:A520 3.7 60.7 1.0 C1' A:A520 3.8 60.7 1.0 C2 A:C519 4.0 68.3 1.0 C2' A:C519 4.3 57.5 1.0 C5' A:A520 4.3 60.7 1.0 C1' A:C519 4.7 57.5 1.0 O2' A:A520 4.7 60.7 1.0 O2' A:U516 4.7 72.8 1.0 N9 A:A520 4.8 67.2 1.0 C2' A:A520 4.8 60.7 1.0 N3 A:C519 4.8 68.3 1.0 N1 A:C519 4.8 68.3 1.0 C3' A:A520 4.9 60.7 1.0

Magnesium binding site 2 out of 96 in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1546 b:35.5 occ:1.35 OP2 A:G945 2.1 55.1 1.0 OP1 A:G944 2.2 47.8 1.0 P A:G944 3.2 45.8 1.0 P A:G945 3.3 49.8 1.0 OP2 A:G944 3.6 47.8 1.0 O5' A:G944 3.7 45.8 1.0 OP1 A:G945 3.7 55.1 1.0 N7 A:A946 4.2 47.9 1.0 C5' A:G944 4.2 45.8 1.0 O5' A:G945 4.3 49.8 1.0 O3' A:G944 4.4 45.8 1.0 O3' A:U943 4.6 40.1 1.0 OP2 A:A946 4.6 47.9 1.0 C3' A:G944 4.7 45.8 1.0 O6 A:G947 4.7 54.1 1.0 C8 A:A946 4.7 47.9 1.0 C5' A:G945 5.0 49.8 1.0

Magnesium binding site 3 out of 96 in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1547 b:35.5 occ:1.42 OP1 A:G1224 1.9 71.0 1.0 P A:G1224 3.1 61.4 1.0 OP2 A:G1224 3.6 71.0 1.0 O2' A:C1223 3.6 57.5 1.0 C2' A:C1223 4.0 57.5 1.0 O3' A:C1223 4.1 57.5 1.0 O5' A:G1224 4.3 61.4 1.0 N7 A:A977 4.4 87.6 1.0 C3' A:C1223 4.6 57.5 1.0 N6 A:A977 4.6 87.6 1.0 OP1 A:G951 4.7 63.3 1.0 OP2 A:U952 4.7 61.3 1.0

Magnesium binding site 4 out of 96 in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1548 b:35.5 occ:0.92 O4 A:U12 2.7 50.5 1.0 O6 A:G22 3.0 39.1 1.0 O6 A:G11 3.1 49.0 1.0 O6 A:G21 3.3 49.2 1.0 N4 A:C23 3.6 42.8 1.0 C4 A:U12 3.7 50.5 1.0 C6 A:G21 3.7 49.2 1.0 N3 A:U12 3.9 50.5 1.0 N1 A:G21 4.0 49.2 1.0 C6 A:G22 4.1 39.1 1.0 C6 A:G11 4.2 49.0 1.0 N7 A:G22 4.4 39.1 1.0 C5 A:G21 4.5 49.2 1.0 C5 A:G22 4.6 39.1 1.0 C4 A:C23 4.7 42.8 1.0 C5 A:U12 5.0 50.5 1.0 C2 A:G21 5.0 49.2 1.0

Magnesium binding site 5 out of 96 in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1549 b:35.5 occ:0.76 O6 A:G741 2.5 54.5 1.0 O6 A:G742 2.9 46.4 1.0 N7 A:G741 3.0 54.5 1.0 C6 A:G741 3.1 54.5 1.0 N7 A:G742 3.3 46.4 1.0 C5 A:G741 3.3 54.5 1.0 O6 A:G664 3.4 50.8 1.0 C6 A:G742 3.5 46.4 1.0 C5 A:G742 3.6 46.4 1.0 C8 A:G741 4.2 54.5 1.0 C6 A:G664 4.3 50.8 1.0 N1 A:G741 4.3 54.5 1.0 N1 A:G664 4.4 50.8 1.0 C8 A:G742 4.4 46.4 1.0 C4 A:G741 4.6 54.5 1.0 N1 A:G742 4.7 46.4 1.0 C4 A:G742 4.8 46.4 1.0 O6 A:G666 4.8 56.7 1.0 N9 A:G741 5.0 54.5 1.0 N6 A:A663 5.0 48.9 1.0

Magnesium binding site 6 out of 96 in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1550 b:35.5 occ:0.59 OP2 A:U17 2.6 43.3 1.0 O4 A:U14 2.9 64.2 1.0 P A:U17 3.6 37.3 1.0 OP1 A:U17 3.7 43.3 1.0 C4 A:U14 3.8 64.2 1.0 N3 A:U14 4.2 64.2 1.0 O5' A:U17 4.6 37.3 1.0 O3' A:A16 4.8 35.0 1.0 C5 A:U14 4.9 64.2 1.0 OP2 A:C18 4.9 33.2 1.0

Magnesium binding site 7 out of 96 in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 7 of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1551 b:35.5 occ:1.14 O6 A:G377 3.2 68.2 1.0 O6 A:G376 3.8 63.1 1.0 N7 A:G377 4.1 68.2 1.0 N7 A:G376 4.2 63.1 1.0 C6 A:G377 4.2 68.2 1.0 C6 A:G376 4.3 63.1 1.0 MG A:MG1600 4.4 35.5 0.8 C5 A:G376 4.5 63.1 1.0 C5 A:G377 4.6 68.2 1.0

Magnesium binding site 8 out of 96 in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 8 of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1552 b:35.5 occ:0.90 OP2 A:G750 2.0 57.1 1.0 OP2 A:C749 2.0 73.1 1.0 P A:C749 3.2 60.1 1.0 P A:G750 3.4 59.7 1.0 OP1 A:C749 3.5 73.1 1.0 O2' A:C748 4.1 90.3 1.0 O3' A:C749 4.1 60.1 1.0 C3' A:C749 4.1 60.1 1.0 O5' A:C749 4.3 60.1 1.0 O3' A:C748 4.3 90.3 1.0 O5' A:G750 4.4 59.7 1.0 OP1 A:G750 4.4 57.1 1.0 N7 A:G750 4.8 57.1 1.0 C2' A:C748 4.9 90.3 1.0 C5' A:C749 4.9 60.1 1.0

Magnesium binding site 9 out of 96 in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 9 of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1553 b:35.5 occ:1.42 OP2 A:A766 2.2 24.8 1.0 O2 A:C812 3.5 38.0 1.0 P A:A766 3.6 42.3 1.0 N4 A:C811 3.8 36.8 1.0 N3 A:C812 4.0 38.0 1.0 N3 A:C811 4.0 36.8 1.0 O4 A:U813 4.1 46.5 1.0 C2 A:C812 4.1 38.0 1.0 O3' A:G765 4.2 40.6 1.0 O5' A:A766 4.3 42.3 1.0 C4 A:C811 4.3 36.8 1.0 C3' A:G765 4.3 40.6 1.0 N6 A:A768 4.7 32.8 1.0 OP1 A:A766 4.8 24.8 1.0 C2' A:G765 4.8 40.6 1.0 C4 A:U813 4.8 46.5 1.0 N7 A:A767 4.9 35.2 1.0

Magnesium binding site 10 out of 96 in the Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 10 of Structure of the Thermus Thermophilus 30S Ribosomal Subunit in Complex with Tetracycline within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1554 b:35.5 occ:1.47 OP2 A:A768 2.2 32.8 1.0 P A:A768 3.6 33.2 1.0 N7 A:A768 4.1 32.8 1.0 OP1 A:U804 4.2 51.4 1.0 O5' A:A768 4.2 33.2 1.0 N7 A:G769 4.4 28.6 1.0 C8 A:A768 4.5 32.8 1.0 O3' A:A767 4.6 51.4 1.0 OP1 A:A768 4.6 32.8 1.0 C3' A:A767 4.6 51.4 1.0 OP2 A:C805 4.7 46.2 1.0 O5' A:A767 4.7 51.4 1.0 OP2 A:A767 4.7 35.2 1.0 O6 A:G769 4.9 28.6 1.0 C5' A:U804 5.0 40.2 1.0

D.E.Brodersen, W.M.Clemons Jr., A.P.Carter, R.J.Morgan-Warren, B.T.Wimberly, V.Ramakrishnan. The Structural Basis For the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit. Cell(Cambridge,Mass.) V. 103 1143 2000.
ISSN: ISSN 0092-8674
PubMed: 11163189
DOI: 10.1016/S0092-8674(00)00216-6