Magnesium in PDB 1jm6: Pyruvate Dehydrogenase Kinase, Isozyme 2, Containing Adp

All present enzymatic activity of Pyruvate Dehydrogenase Kinase, Isozyme 2, Containing Adp:
2.7.1.99;

The structure of Pyruvate Dehydrogenase Kinase, Isozyme 2, Containing Adp, PDB code: 1jm6 was solved by C.N.Steussy, K.M.Popov, M.M.Bowker-Kinley, R.B.Sloan, R.A.Harris, J.A.Hamilton, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	6.00 / 2.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	71.421, 109.874, 71.414, 90.00, 104.52, 90.00
R / Rfree (%)	20.8 / 26.2

The binding sites of Magnesium atom in the Pyruvate Dehydrogenase Kinase, Isozyme 2, Containing Adp (pdb code 1jm6). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Pyruvate Dehydrogenase Kinase, Isozyme 2, Containing Adp, PDB code: 1jm6:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Pyruvate Dehydrogenase Kinase, Isozyme 2, Containing Adp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Pyruvate Dehydrogenase Kinase, Isozyme 2, Containing Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg4601 b:44.3 occ:1.00 O2A A:ADP3500 2.0 31.9 1.0 O A:HOH4602 2.0 51.7 1.0 O A:HOH4603 2.1 49.9 1.0 O3B A:ADP3500 2.2 28.2 1.0 OD1 A:ASN1247 2.7 24.8 1.0 PA A:ADP3500 3.1 34.6 1.0 PB A:ADP3500 3.1 30.7 1.0 O3A A:ADP3500 3.2 29.9 1.0 CG A:ASN1247 3.5 25.1 1.0 ND2 A:ASN1247 3.7 22.0 1.0 O1B A:ADP3500 3.7 27.0 1.0 O1A A:ADP3500 3.8 35.7 1.0 CB A:ALA1316 4.0 56.2 1.0 O A:GLU1243 4.1 29.2 1.0 OE1 A:GLU1243 4.2 39.7 1.0 CA A:GLY1321 4.2 32.1 1.0 O5' A:ADP3500 4.3 36.8 1.0 O A:HOH6072 4.5 20.7 1.0 O A:HOH6218 4.5 28.4 1.0 O2B A:ADP3500 4.6 29.7 1.0 O A:HOH6076 4.6 17.9 1.0 N A:GLY1321 4.6 35.2 1.0 CB A:ASN1247 4.9 27.5 1.0

Magnesium binding site 2 out of 2 in the Pyruvate Dehydrogenase Kinase, Isozyme 2, Containing Adp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Pyruvate Dehydrogenase Kinase, Isozyme 2, Containing Adp within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg4611 b:47.0 occ:1.00 O2A B:ADP3510 2.0 31.9 1.0 O B:HOH6003 2.0 51.3 1.0 O B:HOH6004 2.1 49.6 1.0 O3B B:ADP3510 2.2 28.2 1.0 OD1 B:ASN1247 2.7 31.3 1.0 PA B:ADP3510 3.1 34.6 1.0 PB B:ADP3510 3.1 30.7 1.0 O3A B:ADP3510 3.2 29.9 1.0 CG B:ASN1247 3.6 29.1 1.0 O1B B:ADP3510 3.7 27.0 1.0 ND2 B:ASN1247 3.8 24.9 1.0 O1A B:ADP3510 3.8 35.7 1.0 OE1 B:GLU1243 3.9 39.0 1.0 CA B:GLY1321 4.0 31.8 1.0 O5' B:ADP3510 4.3 36.8 1.0 O B:GLU1243 4.3 30.0 1.0 N B:GLY1321 4.4 31.5 1.0 O2B B:ADP3510 4.6 29.7 1.0 C B:GLY1321 4.7 31.1 1.0 O B:HOH6087 4.7 31.7 1.0 N B:LEU1322 4.8 30.0 1.0 CD1 B:PHE1318 4.9 55.5 1.0 CE B:LYS1246 5.0 28.9 1.0 O B:LEU1315 5.0 58.4 1.0

C.N.Steussy, K.M.Popov, M.M.Bowker-Kinley, R.B.Sloan Jr., R.A.Harris, J.A.Hamilton. Structure of Pyruvate Dehydrogenase Kinase. Novel Folding Pattern For A Serine Protein Kinase. J.Biol.Chem. V. 276 37443 2001.
ISSN: ISSN 0021-9258
PubMed: 11483605
DOI: 10.1074/JBC.M104285200