Magnesium in PDB 1nv1: Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (5 Mm)

All present enzymatic activity of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (5 Mm):
3.1.3.11;

The structure of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (5 Mm), PDB code: 1nv1 was solved by J.Choe, C.V.Iancu, H.J.Fromm, R.B.Honzatko, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	5.00 / 1.90
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	53.074, 82.829, 165.173, 90.00, 90.00, 90.00
R / Rfree (%)	20.3 / 25.5

The structure of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (5 Mm) also contains other interesting chemical elements:

Thallium

(Tl)

6 atoms

The binding sites of Magnesium atom in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (5 Mm) (pdb code 1nv1). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (5 Mm), PDB code: 1nv1:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (5 Mm)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (5 Mm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2341 b:22.8 occ:0.90 TL A:TL2342 0.6 23.5 0.1 O2 A:PO42340 2.0 26.7 1.0 OD1 A:ASP1121 2.0 14.9 1.0 OE1 A:GLU1280 2.1 21.5 1.0 OD1 A:ASP1118 2.2 22.8 1.0 O1 A:F6P2339 2.5 14.2 0.5 CG A:ASP1121 2.9 22.0 1.0 CB A:ASP1121 3.1 18.4 1.0 P A:PO42340 3.2 24.8 1.0 CD A:GLU1280 3.3 27.3 1.0 CG A:ASP1118 3.3 22.5 1.0 CA A:ASP1121 3.4 21.0 1.0 O1 A:PO42340 3.6 14.7 1.0 TL A:TL2344 3.6 8.3 0.1 O3 A:PO42340 3.6 28.3 1.0 C1 A:F6P2339 3.6 19.5 1.0 OD2 A:ASP1118 3.8 16.6 1.0 CG A:GLU1280 3.8 13.9 1.0 O3 A:F6P2339 3.9 19.6 1.0 OD2 A:ASP1121 4.1 18.3 1.0 N A:GLY1122 4.2 18.8 1.0 OE2 A:GLU1280 4.3 19.3 1.0 OE2 A:GLU1097 4.3 20.1 1.0 C A:ASP1121 4.3 24.2 1.0 C3 A:F6P2339 4.4 25.7 1.0 O4 A:PO42340 4.4 40.8 1.0 C2 A:F6P2339 4.4 28.3 1.0 O1 A:F6P2339 4.4 8.3 0.5 MG A:MG2343 4.5 28.6 0.7 CB A:ASP1118 4.5 15.7 1.0 CD1 A:ILE1135 4.5 25.8 1.0 N A:ASP1121 4.6 10.9 1.0 O A:LEU1120 4.6 15.6 1.0 O2 A:F6P2339 4.6 21.3 1.0 TL A:TL2348 4.8 29.2 0.1

Magnesium binding site 2 out of 2 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (5 Mm)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (5 Mm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2343 b:28.6 occ:0.68 TL A:TL2344 0.8 8.3 0.1 OE2 A:GLU1097 2.1 20.1 1.0 O A:LEU1120 2.2 15.6 1.0 OD2 A:ASP1118 2.2 16.6 1.0 O4 A:PO42340 2.5 40.8 1.0 O2 A:PO42340 2.8 26.7 1.0 CD A:GLU1097 3.1 21.7 1.0 P A:PO42340 3.2 24.8 1.0 C A:LEU1120 3.3 10.8 1.0 CG A:ASP1118 3.4 22.5 1.0 OE1 A:GLU1097 3.6 28.2 1.0 OE2 A:GLU1098 3.7 23.2 1.0 TL A:TL2346 3.7 24.2 0.1 TL A:TL2345 3.7 26.9 0.1 OD1 A:ASP1074 3.7 31.5 1.0 N A:LEU1120 3.8 13.5 1.0 OD1 A:ASP1118 3.9 22.8 1.0 CA A:LEU1120 4.1 21.5 1.0 O3 A:PO42340 4.1 28.3 1.0 N A:ASP1121 4.2 10.9 1.0 CA A:ASP1121 4.3 21.0 1.0 CG A:GLU1097 4.3 17.1 1.0 O1 A:PO42340 4.3 14.7 1.0 CD A:PRO1119 4.4 13.2 1.0 MG A:MG2341 4.5 22.8 0.9 CB A:LEU1120 4.5 21.5 1.0 CB A:GLU1097 4.6 14.6 1.0 CB A:ASP1118 4.6 15.7 1.0 CG A:ASP1074 4.6 30.3 1.0 N A:PRO1119 4.6 17.8 1.0 C A:ASP1118 4.7 13.3 1.0 TL A:TL2342 4.7 23.5 0.1 CG A:PRO1119 4.8 13.1 1.0 CA A:ASP1118 4.8 15.5 1.0 CD A:GLU1098 4.8 27.0 1.0

J.Y.Choe, S.W.Nelson, H.J.Fromm, R.B.Honzatko. Interaction of Tl+ with Product Complexes of Fructose-1,6-Bisphosphatase J.Biol.Chem. V. 278 16008 2003.
ISSN: ISSN 0021-9258
PubMed: 12595529
DOI: 10.1074/JBC.M212394200