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Magnesium in PDB 1ob5: T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna
Enzymatic activity of T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna
All present enzymatic activity of T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna:
3.6.1.48;
3.6.1.48;
Protein crystallography data
The structure of T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna, PDB code: 1ob5
was solved by
C.Dahlberg,
R.C.Nielsen,
A.Parmeggiani,
J.Nyborg,
P.Nissen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 29.54 / 3.10 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 212.570, 122.330, 135.680, 90.00, 121.30, 90.00 |
| R / Rfree (%) | 28 / 29.4 |
Other elements in 1ob5:
The structure of T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna also contains other interesting chemical elements:
| Chlorine | (Cl) | 6 atoms |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna
(pdb code 1ob5). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna, PDB code: 1ob5:
Jump to Magnesium binding site number: 1; 2; 3;
In total 3 binding sites of Magnesium where determined in the T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna, PDB code: 1ob5:
Jump to Magnesium binding site number: 1; 2; 3;
Magnesium binding site 1 out of 3 in 1ob5
Go back to
Magnesium Binding Sites List in 1ob5
Magnesium binding site 1 out
of 3 in the T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna within 5.0Å range:
|
Magnesium binding site 2 out of 3 in 1ob5
Go back to
Magnesium Binding Sites List in 1ob5
Magnesium binding site 2 out
of 3 in the T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna within 5.0Å range:
|
Magnesium binding site 3 out of 3 in 1ob5
Go back to
Magnesium Binding Sites List in 1ob5
Magnesium binding site 3 out
of 3 in the T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of T. Aquaticus Elongation Factor Ef-Tu Complexed with the Antibiotic Enacyloxin Iia, A Gtp Analog, and Phe-Trna within 5.0Å range:
|
Reference:
A.Parmeggiani,
I.M.Krab,
T.Watanabe,
R.C.Nielsen,
C.Dahlberg,
J.Nyborg,
P.Nissen.
Enacyloxin Iia Pinpoints A Binding Pocket of Elongation Factor Tu For Development of Novel Antibiotics. J.Biol.Chem. V. 281 2893 2006.
ISSN: ISSN 0021-9258
PubMed: 16257965
DOI: 10.1074/JBC.M505951200
Page generated: Mon Dec 14 06:34:29 2020
ISSN: ISSN 0021-9258
PubMed: 16257965
DOI: 10.1074/JBC.M505951200
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