Magnesium in PDB 1oco: Bovine Heart Cytochrome C Oxidase in Carbon Monoxide-Bound State

All present enzymatic activity of Bovine Heart Cytochrome C Oxidase in Carbon Monoxide-Bound State:
1.9.3.1;

The structure of Bovine Heart Cytochrome C Oxidase in Carbon Monoxide-Bound State, PDB code: 1oco was solved by T.Tsukihara, M.Yao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	7.00 / 2.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	189.100, 210.500, 178.600, 90.00, 90.00, 90.00
R / Rfree (%)	21.3 / 25.6

The structure of Bovine Heart Cytochrome C Oxidase in Carbon Monoxide-Bound State also contains other interesting chemical elements:

Zinc	(Zn)	2 atoms
Iron	(Fe)	4 atoms
Copper	(Cu)	6 atoms
Sodium	(Na)	2 atoms

The binding sites of Magnesium atom in the Bovine Heart Cytochrome C Oxidase in Carbon Monoxide-Bound State (pdb code 1oco). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Bovine Heart Cytochrome C Oxidase in Carbon Monoxide-Bound State, PDB code: 1oco:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Bovine Heart Cytochrome C Oxidase in Carbon Monoxide-Bound State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Bovine Heart Cytochrome C Oxidase in Carbon Monoxide-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg518 b:7.4 occ:1.00 OE1 B:GLU198 2.1 15.5 1.0 OD2 A:ASP369 2.2 20.1 1.0 NE2 A:HIS368 2.2 18.7 1.0 CE1 A:HIS368 2.6 13.7 1.0 CD B:GLU198 3.4 25.1 1.0 CG A:ASP369 3.4 12.0 1.0 CD2 A:HIS368 3.6 23.2 1.0 OD2 B:ASP173 3.8 35.9 1.0 ND1 A:HIS368 3.9 11.5 1.0 OE2 B:GLU198 4.2 28.6 1.0 O B:SER197 4.2 16.0 1.0 OD1 B:ASP173 4.2 27.4 1.0 OD1 A:ASP369 4.3 22.6 1.0 CB A:ASP369 4.3 7.0 1.0 CG A:HIS368 4.4 10.0 1.0 CG B:GLU198 4.4 15.5 1.0 CG B:ASP173 4.4 27.5 1.0 OG1 A:THR294 4.6 12.7 1.0 CB B:GLU198 4.7 7.0 1.0

Magnesium binding site 2 out of 2 in the Bovine Heart Cytochrome C Oxidase in Carbon Monoxide-Bound State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Bovine Heart Cytochrome C Oxidase in Carbon Monoxide-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ N:Mg518 b:19.5 occ:1.00 OE1 O:GLU198 2.1 32.9 1.0 OD2 N:ASP369 2.1 36.2 1.0 NE2 N:HIS368 2.3 35.6 1.0 CE1 N:HIS368 2.6 24.0 1.0 CG N:ASP369 3.4 26.3 1.0 CD O:GLU198 3.4 30.7 1.0 CD2 N:HIS368 3.7 33.5 1.0 ND1 N:HIS368 3.9 22.3 1.0 OD2 O:ASP173 4.0 35.2 1.0 OE2 O:GLU198 4.1 31.9 1.0 OD1 N:ASP369 4.2 27.6 1.0 CB N:ASP369 4.3 14.6 1.0 O O:SER197 4.3 33.1 1.0 OD1 O:ASP173 4.4 32.8 1.0 CG N:HIS368 4.4 25.3 1.0 CG O:GLU198 4.5 24.9 1.0 CG O:ASP173 4.6 30.3 1.0 OG1 N:THR294 4.7 18.3 1.0 CB O:GLU198 4.9 13.2 1.0

S.Yoshikawa, K.Shinzawa-Itoh, R.Nakashima, R.Yaono, E.Yamashita, N.Inoue, M.Yao, M.J.Fei, C.P.Libeu, T.Mizushima, H.Yamaguchi, T.Tomizaki, T.Tsukihara. Redox-Coupled Crystal Structural Changes in Bovine Heart Cytochrome C Oxidase. Science V. 280 1723 1998.
ISSN: ISSN 0036-8075
PubMed: 9624044
DOI: 10.1126/SCIENCE.280.5370.1723