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Atomistry » Magnesium » PDB 1pi3-1q24 » 1pxh » |
Magnesium in PDB 1pxh: Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2Enzymatic activity of Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2
All present enzymatic activity of Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2:
3.1.3.48; Protein crystallography data
The structure of Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2, PDB code: 1pxh
was solved by
J.P.Sun,
A.Fedorov,
S.Y.Lee,
X.L.Guo,
K.Shen,
D.S.Lawrence,
S.C.Almo,
Z.Y.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1pxh:
The structure of Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2
(pdb code 1pxh). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2, PDB code: 1pxh: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 1pxhGo back to Magnesium Binding Sites List in 1pxh
Magnesium binding site 1 out
of 2 in the Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 1pxhGo back to Magnesium Binding Sites List in 1pxh
Magnesium binding site 2 out
of 2 in the Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2
Mono view Stereo pair view
Reference:
J.P.Sun,
A.A.Fedorov,
S.Y.Lee,
X.L.Guo,
K.Shen,
D.S.Lawrence,
S.C.Almo,
Z.Y.Zhang.
Crystal Structure of PTP1B Complexed with A Potent and Selective Bidentate Inhibitor. J.Biol.Chem. V. 278 12406 2003.
Page generated: Tue Aug 13 10:57:30 2024
ISSN: ISSN 0021-9258 PubMed: 12547827 DOI: 10.1074/JBC.M212491200 |
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