Magnesium in PDB 1qgx: X-Ray Structure of Yeast HAL2P

All present enzymatic activity of X-Ray Structure of Yeast HAL2P:
3.1.3.7;

The structure of X-Ray Structure of Yeast HAL2P, PDB code: 1qgx was solved by A.Albert, L.Yenush, M.R.Gil-Mascarell, P.L.Rodriguez, J.Patel, M.Martinez-Ripoll, T.L.Blundell, R.Serrano, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	67.00 / 1.60
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	54.680, 44.910, 71.600, 90.00, 111.08, 90.00
R / Rfree (%)	19.7 / 23.5

The binding sites of Magnesium atom in the X-Ray Structure of Yeast HAL2P (pdb code 1qgx). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the X-Ray Structure of Yeast HAL2P, PDB code: 1qgx:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the X-Ray Structure of Yeast HAL2P


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of X-Ray Structure of Yeast HAL2P within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg401 b:13.0 occ:1.00 OD1 A:ASP142 2.2 8.8 1.0 OE1 A:GLU72 2.2 12.3 1.0 O A:HOH410 2.3 10.8 1.0 O3 A:PO4404 2.3 14.2 1.0 O2 A:PO4404 2.3 16.1 1.0 O A:ILE144 2.4 11.4 1.0 P A:PO4404 3.0 24.1 1.0 CG A:ASP142 3.1 12.4 1.0 CD A:GLU72 3.3 14.6 1.0 C A:ILE144 3.3 10.7 1.0 OD2 A:ASP142 3.4 12.2 1.0 OE2 A:GLU72 3.7 14.7 1.0 O1 A:PO4404 3.8 17.7 1.0 MG A:MG403 3.9 18.1 1.0 CA A:ASP145 4.0 9.9 1.0 N A:ASP145 4.0 8.4 1.0 O4 A:PO4404 4.0 15.2 1.0 OG1 A:THR147 4.0 11.5 1.0 N A:ILE144 4.1 10.4 1.0 OE2 A:GLU73 4.2 11.5 1.0 OD2 A:ASP49 4.2 10.5 1.0 CA A:ILE144 4.3 9.9 1.0 CB A:ASP142 4.4 10.6 1.0 CD A:PRO143 4.5 10.8 1.0 O A:HOH760 4.5 16.1 1.0 CG A:GLU72 4.5 11.7 1.0 O A:HOH408 4.5 19.4 1.0 O3' A:AMP405 4.6 15.7 1.0 CA A:ASP142 4.6 9.3 1.0 CB A:GLU72 4.6 10.6 1.0 N A:PRO143 4.6 9.2 1.0 C A:ASP142 4.7 9.0 1.0 N A:GLY146 4.8 10.4 1.0 CB A:ILE144 4.8 11.2 1.0 C A:ASP145 4.9 6.6 1.0 CG A:PRO143 4.9 11.1 1.0 CB A:ASP145 5.0 12.1 1.0

Magnesium binding site 2 out of 2 in the X-Ray Structure of Yeast HAL2P


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of X-Ray Structure of Yeast HAL2P within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg403 b:18.1 occ:1.00 OE2 A:GLU72 2.3 14.7 1.0 O A:HOH408 2.3 19.4 1.0 O1 A:PO4404 2.4 17.7 1.0 O A:HOH409 2.4 18.4 1.0 O A:HOH411 2.5 25.3 1.0 O2 A:PO4404 2.5 16.1 1.0 P A:PO4404 3.0 24.1 1.0 CD A:GLU72 3.3 14.6 1.0 OE1 A:GLU72 3.6 12.3 1.0 NZ A:LYS39 3.7 17.8 1.0 O A:PRO44 3.8 14.3 1.0 MG A:MG401 3.9 13.0 1.0 O1 A:SO4406 3.9 21.6 1.0 O A:HOH760 3.9 16.1 1.0 O3 A:PO4404 3.9 14.2 1.0 OE2 A:GLU73 4.0 11.5 1.0 O4 A:PO4404 4.0 15.2 1.0 OG A:SER43 4.1 12.2 1.0 CE A:LYS39 4.1 19.9 1.0 O2 A:SO4406 4.2 23.8 1.0 O A:HOH759 4.3 31.7 1.0 OG1 A:THR147 4.3 11.5 1.0 O A:HOH410 4.5 10.8 1.0 S A:SO4406 4.6 21.1 1.0 CB A:SER43 4.6 13.5 1.0 CG A:GLU72 4.6 11.7 1.0 O A:HOH758 4.6 21.6 1.0 CD A:GLU73 4.9 11.0 1.0 CB A:THR147 4.9 10.9 1.0

A.Albert, L.Yenush, M.R.Gil-Mascarell, P.L.Rodriguez, S.Patel, M.Martinez-Ripoll, T.L.Blundell, R.Serrano. X-Ray Structure of Yeast HAL2P, A Major Target of Lithium and Sodium Toxicity, and Identification of Framework Interactions Determining Cation Sensitivity. J.Mol.Biol. V. 295 927 2000.
ISSN: ISSN 0022-2836
PubMed: 10656801
DOI: 10.1006/JMBI.1999.3408