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Atomistry » Magnesium » PDB 1so6-1t5s » 1t05 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 1so6-1t5s » 1t05 » |
Magnesium in PDB 1t05: Hiv-1 Reverse Transcriptase Crosslinked to Template-Primer with Tenofovir-Diphosphate Bound As the Incoming Nucleotide SubstrateEnzymatic activity of Hiv-1 Reverse Transcriptase Crosslinked to Template-Primer with Tenofovir-Diphosphate Bound As the Incoming Nucleotide Substrate
All present enzymatic activity of Hiv-1 Reverse Transcriptase Crosslinked to Template-Primer with Tenofovir-Diphosphate Bound As the Incoming Nucleotide Substrate:
2.7.7.49; Protein crystallography data
The structure of Hiv-1 Reverse Transcriptase Crosslinked to Template-Primer with Tenofovir-Diphosphate Bound As the Incoming Nucleotide Substrate, PDB code: 1t05
was solved by
S.Tuske,
S.G.Sarafianos,
J.Ding,
E.Arnold,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Hiv-1 Reverse Transcriptase Crosslinked to Template-Primer with Tenofovir-Diphosphate Bound As the Incoming Nucleotide Substrate
(pdb code 1t05). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Hiv-1 Reverse Transcriptase Crosslinked to Template-Primer with Tenofovir-Diphosphate Bound As the Incoming Nucleotide Substrate, PDB code: 1t05: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 1t05Go back to Magnesium Binding Sites List in 1t05
Magnesium binding site 1 out
of 2 in the Hiv-1 Reverse Transcriptase Crosslinked to Template-Primer with Tenofovir-Diphosphate Bound As the Incoming Nucleotide Substrate
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 1t05Go back to Magnesium Binding Sites List in 1t05
Magnesium binding site 2 out
of 2 in the Hiv-1 Reverse Transcriptase Crosslinked to Template-Primer with Tenofovir-Diphosphate Bound As the Incoming Nucleotide Substrate
Mono view Stereo pair view
Reference:
S.Tuske,
S.G.Sarafianos,
A.D.Clark Jr.,
J.Ding,
L.K.Naeger,
K.L.White,
M.D.Miller,
C.S.Gibbs,
P.L.Boyer,
P.Clark,
G.Wang,
B.L.Gaffney,
R.A.Jones,
D.M.Jerina,
S.H.Hughes,
E.Arnold.
Structures of Hiv-1 Rt-Dna Complexes Before and After Incorporation of the Anti-Aids Drug Tenofovir Nat.Struct.Mol.Biol. V. 11 469 2004.
Page generated: Tue Aug 13 14:24:04 2024
ISSN: ISSN 1545-9993 PubMed: 15107837 DOI: 10.1038/NSMB760 |
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