Magnesium in PDB 1t3n: Structure of the Catalytic Core of Dna Polymerase Iota in Complex with Dna and Dttp

The structure of Structure of the Catalytic Core of Dna Polymerase Iota in Complex with Dna and Dttp, PDB code: 1t3n was solved by D.T.Nair, R.E.Johnson, S.Prakash, L.Prakash, A.K.Aggarwal, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.30
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	98.831, 98.831, 202.755, 90.00, 90.00, 120.00
R / Rfree (%)	26.5 / 28.6

The binding sites of Magnesium atom in the Structure of the Catalytic Core of Dna Polymerase Iota in Complex with Dna and Dttp (pdb code 1t3n). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of the Catalytic Core of Dna Polymerase Iota in Complex with Dna and Dttp, PDB code: 1t3n:

Magnesium binding site 1 out of 1 in the Structure of the Catalytic Core of Dna Polymerase Iota in Complex with Dna and Dttp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the Catalytic Core of Dna Polymerase Iota in Complex with Dna and Dttp within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg901 b:35.6 occ:0.50 OD1 B:ASP546 2.1 51.7 0.5 O1G B:TTP902 2.1 34.7 0.5 O1A B:TTP902 2.2 32.9 0.5 OD2 B:ASP454 2.2 27.6 0.5 O2B B:TTP902 2.4 33.7 0.5 O B:LEU455 2.6 31.3 0.5 CG B:ASP546 3.1 46.1 0.5 CG B:ASP454 3.3 28.5 0.5 PA B:TTP902 3.4 36.0 0.5 PB B:TTP902 3.4 33.6 0.5 PG B:TTP902 3.4 32.9 0.5 OD2 B:ASP546 3.5 51.1 0.5 O3B B:TTP902 3.7 36.0 0.5 O B:HOH1118 3.8 30.7 0.5 OD1 B:ASP454 3.8 30.0 0.5 C B:LEU455 3.8 31.5 0.5 O3A B:TTP902 3.9 37.8 0.5 N B:LEU455 4.1 28.0 0.5 O5' B:TTP902 4.1 33.3 0.5 O2A B:TTP902 4.2 38.0 0.5 C5' B:TTP902 4.2 33.2 0.5 O3G B:TTP902 4.3 35.3 0.5 CB B:ASP546 4.3 41.6 0.5 C B:ASP454 4.5 28.2 0.5 CA B:LEU455 4.5 30.4 0.5 O2G B:TTP902 4.5 37.7 0.5 CB B:ASP454 4.6 27.7 0.5 O B:ASP546 4.7 36.2 0.5 CA B:ASP454 4.8 27.0 0.5 O1B B:TTP902 4.8 38.1 0.5 N B:ASP456 4.9 30.2 0.5 N B:CYS457 5.0 28.8 0.5 O B:ASP454 5.0 31.4 0.5

D.T.Nair, R.E.Johnson, S.Prakash, L.Prakash, A.K.Aggarwal. Replication By Human Dna Polymerase-Iota Occurs By Hoogsteen Base-Pairing. Nature V. 430 377 2004.
ISSN: ISSN 0028-0836
PubMed: 15254543
DOI: 10.1038/NATURE02692