Magnesium in PDB 1tzd: Crystal Structure of the Catalytic Core of Inositol 1,4,5- Trisphosphate 3-Kinase

All present enzymatic activity of Crystal Structure of the Catalytic Core of Inositol 1,4,5- Trisphosphate 3-Kinase:
2.7.1.127;

The structure of Crystal Structure of the Catalytic Core of Inositol 1,4,5- Trisphosphate 3-Kinase, PDB code: 1tzd was solved by G.J.Miller, J.H.Hurley, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.92 / 2.20
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	71.679, 98.535, 188.745, 90.00, 90.00, 90.00
R / Rfree (%)	25.7 / 30.5

The binding sites of Magnesium atom in the Crystal Structure of the Catalytic Core of Inositol 1,4,5- Trisphosphate 3-Kinase (pdb code 1tzd). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the Catalytic Core of Inositol 1,4,5- Trisphosphate 3-Kinase, PDB code: 1tzd:

Magnesium binding site 1 out of 1 in the Crystal Structure of the Catalytic Core of Inositol 1,4,5- Trisphosphate 3-Kinase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Catalytic Core of Inositol 1,4,5- Trisphosphate 3-Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2 b:56.4 occ:1.00 O B:HOH472 2.3 37.0 1.0 O B:HOH634 2.4 75.9 1.0 OD1 B:ASP414 2.6 43.5 1.0 O3A B:ADP1 2.7 75.5 1.0 O2B B:ADP1 2.7 75.1 1.0 PB B:ADP1 3.2 74.0 1.0 CG B:ASP414 3.7 40.5 1.0 O5' B:ADP1 3.9 73.0 1.0 O B:GLY395 3.9 31.9 1.0 O1B B:ADP1 4.0 74.0 1.0 PA B:ADP1 4.0 74.5 1.0 C5' B:ADP1 4.1 68.3 1.0 CB B:ASP414 4.1 36.9 1.0 NZ B:LYS262 4.3 42.4 1.0 CE B:LYS262 4.3 44.0 1.0 OD2 B:ASP260 4.4 38.9 1.0 O B:HOH556 4.5 46.2 1.0 O3B B:ADP1 4.6 73.5 1.0 O2A B:ADP1 4.6 73.8 1.0 OG B:SER397 4.7 38.8 1.0 OD2 B:ASP414 4.8 42.5 1.0 CB B:SER397 5.0 31.9 1.0

G.J.Miller, J.H.Hurley. Crystal Structure of the Catalytic Core of Inositol 1,4,5-Trisphosphate 3-Kinase Mol.Cell V. 15 703 2004.
ISSN: ISSN 1097-2765
PubMed: 15350215
DOI: 10.1016/J.MOLCEL.2004.08.005