Magnesium in PDB 1uby: Structure of Farnesyl Pyrophosphate Synthetase

All present enzymatic activity of Structure of Farnesyl Pyrophosphate Synthetase:
2.5.1.1;

The structure of Structure of Farnesyl Pyrophosphate Synthetase, PDB code: 1uby was solved by L.C.Tarshis, P.Proteau, C.D.Poulter, J.C.Sacchettini, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	N/A / 2.40
Space group	I 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	88.300, 88.300, 274.700, 90.00, 90.00, 90.00
R / Rfree (%)	20.2 / n/a

The binding sites of Magnesium atom in the Structure of Farnesyl Pyrophosphate Synthetase (pdb code 1uby). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Farnesyl Pyrophosphate Synthetase, PDB code: 1uby:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of Farnesyl Pyrophosphate Synthetase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Farnesyl Pyrophosphate Synthetase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg402 b:48.8 occ:1.00 OD2 A:ASP117 1.8 44.9 1.0 O3A A:DMA401 2.4 79.5 1.0 OD2 A:ASP121 2.4 42.6 1.0 O1A A:DMA401 2.9 59.6 1.0 CG A:ASP117 2.9 37.2 1.0 PA A:DMA401 3.3 74.0 1.0 O2B A:DMA401 3.3 82.8 1.0 PB A:DMA401 3.4 79.5 1.0 CG A:ASP121 3.4 38.4 1.0 OD1 A:ASP117 3.4 39.3 1.0 CB A:ASP121 3.8 38.0 1.0 MG A:MG403 4.1 44.7 1.0 CB A:ASP117 4.2 25.0 1.0 OG A:SER123 4.2 30.3 1.0 O1B A:DMA401 4.2 85.7 1.0 O A:ASP117 4.3 20.6 1.0 O1 A:DMA401 4.3 67.1 1.0 C A:ASP117 4.3 24.8 1.0 OD1 A:ASP118 4.4 22.9 1.0 C1 A:DMA401 4.4 66.0 1.0 OD1 A:ASP121 4.5 41.9 1.0 O2A A:DMA401 4.6 78.9 1.0 O3B A:DMA401 4.7 91.4 1.0 CA A:ASP117 4.8 23.9 1.0 NH1 A:ARG126 4.9 29.2 1.0 N A:ASP118 4.9 19.2 1.0

Magnesium binding site 2 out of 2 in the Structure of Farnesyl Pyrophosphate Synthetase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Farnesyl Pyrophosphate Synthetase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg403 b:44.7 occ:1.00 O1A A:DMA401 2.0 59.6 1.0 OD1 A:ASP117 2.3 39.3 1.0 OD2 A:ASP121 2.9 42.6 1.0 OD2 A:ASP188 3.2 59.0 1.0 CG A:ASP117 3.4 37.2 1.0 O A:HOH418 3.4 44.0 1.0 PA A:DMA401 3.5 74.0 1.0 OD1 A:ASP121 3.6 41.9 1.0 CG A:ASP121 3.6 38.4 1.0 NE2 A:GLN185 3.7 32.8 1.0 OD2 A:ASP117 3.9 44.9 1.0 CD1 A:LEU189 3.9 33.5 1.0 O1 A:DMA401 4.1 67.1 1.0 MG A:MG402 4.1 48.8 1.0 C1 A:DMA401 4.2 66.0 1.0 OE1 A:GLN185 4.2 42.8 1.0 O2A A:DMA401 4.2 78.9 1.0 CD A:GLN185 4.3 32.0 1.0 CG A:ASP188 4.3 46.7 1.0 O3A A:DMA401 4.5 79.5 1.0 CB A:ASP117 4.6 25.0 1.0 CB A:ASP188 4.8 42.1 1.0 O A:HOH438 4.9 49.6 1.0 CA A:ASP117 5.0 23.9 1.0

L.C.Tarshis, P.J.Proteau, B.A.Kellogg, J.C.Sacchettini, C.D.Poulter. Regulation of Product Chain Length By Isoprenyl Diphosphate Synthases. Proc.Natl.Acad.Sci.Usa V. 93 15018 1996.
ISSN: ISSN 0027-8424
PubMed: 8986756
DOI: 10.1073/PNAS.93.26.15018