Magnesium in PDB 1xl6: Intermediate Gating Structure 2 of the Inwardly Rectifying K+ Channel KIRBAC3.1

The structure of Intermediate Gating Structure 2 of the Inwardly Rectifying K+ Channel KIRBAC3.1, PDB code: 1xl6 was solved by J.M.Gulbis, A.Kuo, B.Smith, D.A.Doyle, A.Edwards, C.Arrowsmith, M.Sundstrom, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.85
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	105.756, 107.532, 89.654, 90.00, 90.00, 90.00
R / Rfree (%)	27 / 31

The structure of Intermediate Gating Structure 2 of the Inwardly Rectifying K+ Channel KIRBAC3.1 also contains other interesting chemical elements:

Potassium

(K)

7 atoms

The binding sites of Magnesium atom in the Intermediate Gating Structure 2 of the Inwardly Rectifying K+ Channel KIRBAC3.1 (pdb code 1xl6). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Intermediate Gating Structure 2 of the Inwardly Rectifying K+ Channel KIRBAC3.1, PDB code: 1xl6:

Magnesium binding site 1 out of 1 in the Intermediate Gating Structure 2 of the Inwardly Rectifying K+ Channel KIRBAC3.1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Intermediate Gating Structure 2 of the Inwardly Rectifying K+ Channel KIRBAC3.1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2001 b:57.8 occ:0.50 K A:K1003 1.1 25.2 0.5 O A:HOH2003 2.0 62.5 0.5 OG1 A:THR96 2.7 48.6 1.0 OG1 B:THR96 2.8 48.0 1.0 O A:THR96 3.6 48.8 1.0 O B:THR96 3.7 45.5 1.0 K A:K1006 3.9 16.0 0.5 CB A:THR96 3.9 48.0 1.0 CB B:THR96 4.0 45.6 1.0 O B:HOH3004 4.1 38.2 1.0 O B:HOH3011 4.1 49.0 1.0 O B:ALA95 4.3 46.5 1.0 O A:ALA95 4.4 49.0 1.0 C B:THR96 4.4 47.0 1.0 C A:THR96 4.4 49.7 1.0 K B:K1005 4.7 63.2 0.5 CA B:THR96 4.8 46.7 1.0 CA A:THR96 4.8 49.3 1.0 CG2 A:THR96 4.8 48.2 1.0 CG2 B:THR96 5.0 45.6 1.0

J.M.Gulbis, A.Kuo, B.Smith, D.A.Doyle, A.Edwards, C.Arrowsmith, M.Sundstrom. Two Intermediate Gating State Crystal Structures of the KIRBAC3.1 K+ Channel To Be Published.