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Atomistry » Magnesium » PDB 1xfy-1xon » 1xmu » |
Magnesium in PDB 1xmu: Catalytic Domain of Human Phosphodiesterase 4B in Complex with RoflumilastEnzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast
All present enzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast:
3.1.4.17; Protein crystallography data
The structure of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast, PDB code: 1xmu
was solved by
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1xmu:
The structure of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast
(pdb code 1xmu). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast, PDB code: 1xmu: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 1xmuGo back to Magnesium Binding Sites List in 1xmu
Magnesium binding site 1 out
of 2 in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 1xmuGo back to Magnesium Binding Sites List in 1xmu
Magnesium binding site 2 out
of 2 in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Roflumilast
Mono view Stereo pair view
Reference:
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang.
Structural Basis For the Activity of Drugs That Inhibit Phosphodiesterases. Structure V. 12 2233 2004.
Page generated: Tue Aug 13 17:44:39 2024
ISSN: ISSN 0969-2126 PubMed: 15576036 DOI: 10.1016/J.STR.2004.10.004 |
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