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Atomistry » Magnesium » PDB 1xoq-1xyc » 1xoq | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 1xoq-1xyc » 1xoq » |
Magnesium in PDB 1xoq: Catalytic Domain of Human Phosphodiesterase 4D in Complex with RoflumilastEnzymatic activity of Catalytic Domain of Human Phosphodiesterase 4D in Complex with Roflumilast
All present enzymatic activity of Catalytic Domain of Human Phosphodiesterase 4D in Complex with Roflumilast:
3.1.4.17; Protein crystallography data
The structure of Catalytic Domain of Human Phosphodiesterase 4D in Complex with Roflumilast, PDB code: 1xoq
was solved by
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1xoq:
The structure of Catalytic Domain of Human Phosphodiesterase 4D in Complex with Roflumilast also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Catalytic Domain of Human Phosphodiesterase 4D in Complex with Roflumilast
(pdb code 1xoq). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Catalytic Domain of Human Phosphodiesterase 4D in Complex with Roflumilast, PDB code: 1xoq: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 1xoqGo back to Magnesium Binding Sites List in 1xoq
Magnesium binding site 1 out
of 2 in the Catalytic Domain of Human Phosphodiesterase 4D in Complex with Roflumilast
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 1xoqGo back to Magnesium Binding Sites List in 1xoq
Magnesium binding site 2 out
of 2 in the Catalytic Domain of Human Phosphodiesterase 4D in Complex with Roflumilast
Mono view Stereo pair view
Reference:
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang.
Structural Basis For the Activity of Drugs That Inhibit Phosphodiesterases. Structure V. 12 2233 2004.
Page generated: Mon Dec 14 07:05:21 2020
ISSN: ISSN 0969-2126 PubMed: 15576036 DOI: 10.1016/J.STR.2004.10.004 |
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