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Atomistry » Magnesium » PDB 1xoq-1xyc » 1xos » |
Magnesium in PDB 1xos: Catalytic Domain of Human Phosphodiesterase 4B in Complex with SildenafilEnzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Sildenafil
All present enzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Sildenafil:
3.1.4.17; Protein crystallography data
The structure of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Sildenafil, PDB code: 1xos
was solved by
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1xos:
The structure of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Sildenafil also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Sildenafil
(pdb code 1xos). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Sildenafil, PDB code: 1xos: Magnesium binding site 1 out of 1 in 1xosGo back to Magnesium Binding Sites List in 1xos
Magnesium binding site 1 out
of 1 in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Sildenafil
Mono view Stereo pair view
Reference:
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang.
Structural Basis For the Activity of Drugs That Inhibit Phosphodiesterases. Structure V. 12 2233 2004.
Page generated: Mon Dec 14 07:05:24 2020
ISSN: ISSN 0969-2126 PubMed: 15576036 DOI: 10.1016/J.STR.2004.10.004 |
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