Magnesium in PDB 1yl5: Crystal Structure of Mycobacterium Tuberculosis Dihydrodipicolinate Reductase (RV2773C) (Crystal Form A)

All present enzymatic activity of Crystal Structure of Mycobacterium Tuberculosis Dihydrodipicolinate Reductase (RV2773C) (Crystal Form A):
1.3.1.26;

The structure of Crystal Structure of Mycobacterium Tuberculosis Dihydrodipicolinate Reductase (RV2773C) (Crystal Form A), PDB code: 1yl5 was solved by R.Janowski, G.Kefala, M.S.Weiss, Tb Structural Genomics Consortium(Tbsgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.30
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	59.260, 122.000, 77.930, 90.00, 90.00, 90.00
R / Rfree (%)	20.5 / 24.9

The binding sites of Magnesium atom in the Crystal Structure of Mycobacterium Tuberculosis Dihydrodipicolinate Reductase (RV2773C) (Crystal Form A) (pdb code 1yl5). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Mycobacterium Tuberculosis Dihydrodipicolinate Reductase (RV2773C) (Crystal Form A), PDB code: 1yl5:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Mycobacterium Tuberculosis Dihydrodipicolinate Reductase (RV2773C) (Crystal Form A)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Mycobacterium Tuberculosis Dihydrodipicolinate Reductase (RV2773C) (Crystal Form A) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg246 b:52.6 occ:1.00 O A:LEU26 2.3 53.5 1.0 O A:VAL20 2.4 58.9 1.0 O A:ALA23 2.4 57.9 1.0 O A:ALA21 2.6 61.2 1.0 C A:ALA21 3.2 60.3 1.0 O A:HOH256 3.3 51.5 1.0 C A:LEU26 3.4 54.3 1.0 C A:VAL20 3.5 59.0 1.0 C A:ALA23 3.5 58.2 1.0 CA A:ALA21 3.6 60.0 1.0 N A:ALA23 3.8 58.8 1.0 N A:ALA21 4.0 59.2 1.0 CA A:ALA23 4.1 58.5 1.0 O A:HOH262 4.2 51.9 1.0 N A:ALA22 4.2 60.4 1.0 C A:ALA22 4.3 59.7 1.0 N A:THR27 4.3 53.8 1.0 CA A:THR27 4.3 54.9 1.0 CA A:LEU26 4.4 54.4 1.0 N A:LEU26 4.4 55.6 1.0 CB A:ALA23 4.5 58.4 1.0 N A:ASP24 4.5 58.9 1.0 CG1 A:VAL20 4.6 59.9 1.0 CB A:LEU26 4.7 53.3 1.0 CA A:VAL20 4.7 58.5 1.0 CA A:ALA22 4.8 59.9 1.0 O A:ALA22 4.8 60.2 1.0 CE A:MET1 4.8 75.0 1.0 CA A:ASP24 4.9 59.4 1.0 C A:ASP24 5.0 59.5 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Mycobacterium Tuberculosis Dihydrodipicolinate Reductase (RV2773C) (Crystal Form A)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Mycobacterium Tuberculosis Dihydrodipicolinate Reductase (RV2773C) (Crystal Form A) within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg246 b:60.0 occ:1.00 O B:VAL20 2.2 50.6 1.0 O B:LEU26 2.3 50.3 1.0 O B:ALA23 2.3 53.8 1.0 O B:ALA21 2.7 51.3 1.0 C B:ALA21 3.3 50.8 1.0 C B:VAL20 3.4 50.1 1.0 C B:ALA23 3.4 53.7 1.0 C B:LEU26 3.5 51.0 1.0 CA B:ALA21 3.7 50.3 1.0 N B:ALA23 3.8 52.4 1.0 N B:ALA21 4.0 50.4 1.0 CA B:ALA23 4.1 53.1 1.0 N B:ALA22 4.3 50.8 1.0 N B:LEU26 4.3 53.4 1.0 CA B:LEU26 4.3 51.9 1.0 CB B:ALA23 4.3 52.9 1.0 C B:ALA22 4.3 52.1 1.0 N B:THR27 4.4 49.9 1.0 N B:ASP24 4.5 55.3 1.0 CA B:THR27 4.5 50.0 1.0 CB B:LEU26 4.6 51.3 1.0 CA B:VAL20 4.6 49.3 1.0 CG1 B:VAL20 4.7 50.5 1.0 CA B:ALA22 4.8 51.1 1.0 CA B:ASP24 4.8 56.5 1.0 O B:ALA22 4.9 53.2 1.0

R.Janowski, G.Kefala, M.S.Weiss. The Structure of Dihydrodipicolinate Reductase (Dapb) From Mycobacterium Tuberculosis in Three Crystal Forms. Acta Crystallogr.,Sect.D V. 66 61 2010.
ISSN: ISSN 0907-4449
PubMed: 20057050
DOI: 10.1107/S0907444909043960