Magnesium in PDB 2a42: Actin-Dnase I Complex

All present enzymatic activity of Actin-Dnase I Complex:
3.1.21.1;

The structure of Actin-Dnase I Complex, PDB code: 2a42 was solved by D.Chereau, F.Kerff, R.Dominguez, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.70 / 1.85
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	152.729, 41.484, 117.905, 90.00, 109.28, 90.00
R / Rfree (%)	16.1 / 19.9

The structure of Actin-Dnase I Complex also contains other interesting chemical elements:

Calcium

(Ca)

2 atoms

The binding sites of Magnesium atom in the Actin-Dnase I Complex (pdb code 2a42). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Actin-Dnase I Complex, PDB code: 2a42:

Magnesium binding site 1 out of 1 in the Actin-Dnase I Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Actin-Dnase I Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1273 b:46.2 occ:1.00 O B:ASP198 2.3 43.3 1.0 O B:HOH1303 2.3 34.3 1.0 O B:HOH1381 2.4 34.5 1.0 OD2 B:ASP172 2.4 44.4 1.0 O B:HOH1366 2.4 38.2 1.0 O B:HOH1309 2.5 32.9 1.0 CG B:ASP172 3.3 43.7 1.0 C B:ASP198 3.5 44.1 1.0 OD1 B:ASP172 3.5 46.4 1.0 O B:ASN208 4.1 41.6 1.0 CA B:SER199 4.2 43.4 1.0 N B:ALA210 4.2 41.9 1.0 N B:SER199 4.3 41.4 1.0 C B:SER199 4.4 43.3 1.0 CB B:ALA210 4.5 41.6 1.0 O B:ALA200 4.5 41.5 1.0 CA B:ASP198 4.6 44.3 1.0 O B:SER199 4.7 44.2 1.0 CA B:CYS209 4.7 42.2 1.0 CB B:ASP172 4.7 39.5 1.0 CB B:ASP198 4.8 45.8 1.0 ND2 B:ASN208 4.8 36.3 1.0 C B:CYS209 4.9 42.1 1.0 C B:ASN208 4.9 41.1 1.0 N B:ALA200 4.9 42.7 1.0

D.Chereau, F.Kerff, P.Graceffa, Z.Grabarek, K.Langsetmo, R.Dominguez. Actin-Bound Structures of Wiskott-Aldrich Syndrome Protein (Wasp)-Homology Domain 2 and the Implications For Filament Assembly Proc.Natl.Acad.Sci.Usa V. 102 16644 2005.
ISSN: ISSN 0027-8424
PubMed: 16275905
DOI: 10.1073/PNAS.0507021102