Magnesium in PDB 2acx: Crystal Structure of G Protein Coupled Receptor Kinase 6 Bound to Amppnp

The structure of Crystal Structure of G Protein Coupled Receptor Kinase 6 Bound to Amppnp, PDB code: 2acx was solved by D.T.Lodowski, V.M.Tesmer, J.L.Benovic, J.J.Tesmer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	120.164, 59.270, 221.095, 90.00, 102.58, 90.00
R / Rfree (%)	20.2 / 24.3

The binding sites of Magnesium atom in the Crystal Structure of G Protein Coupled Receptor Kinase 6 Bound to Amppnp (pdb code 2acx). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of G Protein Coupled Receptor Kinase 6 Bound to Amppnp, PDB code: 2acx:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of G Protein Coupled Receptor Kinase 6 Bound to Amppnp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of G Protein Coupled Receptor Kinase 6 Bound to Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg578 b:92.7 occ:1.00 O2A A:ANP577 2.2 81.3 1.0 O2G A:ANP577 2.2 0.1 1.0 O3A A:ANP577 2.5 89.8 1.0 PA A:ANP577 2.9 76.4 1.0 PG A:ANP577 3.0 0.7 1.0 O3G A:ANP577 3.1 0.6 1.0 N3B A:ANP577 3.5 0.5 1.0 PB A:ANP577 3.6 98.2 1.0 O5' A:ANP577 3.8 73.7 1.0 C5' A:ANP577 3.9 69.8 1.0 O1A A:ANP577 4.1 78.3 1.0 O2B A:ANP577 4.4 0.3 1.0 O1G A:ANP577 4.4 0.7 1.0 OD2 A:ASP329 4.6 81.1 1.0 O3' A:ANP577 4.8 65.9 1.0 O1B A:ANP577 4.8 99.7 1.0 O A:LYS194 4.9 69.8 1.0 CA A:GLY195 4.9 69.5 1.0 C3' A:ANP577 4.9 65.1 1.0 C4' A:ANP577 5.0 66.5 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of G Protein Coupled Receptor Kinase 6 Bound to Amppnp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of G Protein Coupled Receptor Kinase 6 Bound to Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg578 b:87.3 occ:1.00 O2A B:ANP577 2.2 77.2 1.0 O2G B:ANP577 2.2 92.4 1.0 O3A B:ANP577 2.7 81.8 1.0 PA B:ANP577 3.0 76.1 1.0 PG B:ANP577 3.7 93.4 1.0 C5' B:ANP577 4.0 67.1 1.0 O5' B:ANP577 4.0 70.3 1.0 PB B:ANP577 4.2 88.1 1.0 O3' B:ANP577 4.2 60.5 1.0 O1A B:ANP577 4.3 77.0 1.0 O1G B:ANP577 4.4 94.0 1.0 N3B B:ANP577 4.5 89.8 1.0 C3' B:ANP577 4.5 63.0 1.0 O3G B:ANP577 4.6 92.1 1.0 OD2 B:ASP329 4.7 68.7 1.0 O2B B:ANP577 4.8 89.3 1.0 C4' B:ANP577 4.8 63.8 1.0 OD1 B:ASN316 5.0 64.0 1.0

D.T.Lodowski, V.M.Tesmer, J.L.Benovic, J.J.Tesmer. The Structure of G Protein-Coupled Receptor Kinase (Grk)-6 Defines A Second Lineage of Grks. J.Biol.Chem. V. 281 16785 2006.
ISSN: ISSN 0021-9258
PubMed: 16613860
DOI: 10.1074/JBC.M601327200