Magnesium in PDB 2anr: Crystal Structure (II) of Nova-1 KH1/KH2 Domain Tandem with 25NT Rna Hairpin

The structure of Crystal Structure (II) of Nova-1 KH1/KH2 Domain Tandem with 25NT Rna Hairpin, PDB code: 2anr was solved by L.Malinina, M.Teplova, K.Musunuru, A.Teplov, J.C.Darnell, S.K.Burley, R.B.Darnell, D.J.Patel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.94
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	159.453, 37.885, 38.523, 90.00, 96.64, 90.00
R / Rfree (%)	22.7 / 26.8

The structure of Crystal Structure (II) of Nova-1 KH1/KH2 Domain Tandem with 25NT Rna Hairpin also contains other interesting chemical elements:

Potassium	(K)	1 atom
Bromine	(Br)	1 atom

The binding sites of Magnesium atom in the Crystal Structure (II) of Nova-1 KH1/KH2 Domain Tandem with 25NT Rna Hairpin (pdb code 2anr). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure (II) of Nova-1 KH1/KH2 Domain Tandem with 25NT Rna Hairpin, PDB code: 2anr:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure (II) of Nova-1 KH1/KH2 Domain Tandem with 25NT Rna Hairpin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure (II) of Nova-1 KH1/KH2 Domain Tandem with 25NT Rna Hairpin within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg302 b:15.6 occ:0.50 O B:HOH303 2.1 21.0 1.0 O6 B:G207 2.2 18.9 1.0 O B:HOH321 2.3 21.3 1.0 O B:HOH334 2.8 24.6 1.0 O B:HOH324 3.1 25.7 1.0 K B:K301 3.1 19.1 0.5 C6 B:G207 3.3 20.7 1.0 N7 B:G207 3.8 24.1 1.0 C5 B:G207 3.9 17.6 1.0 N7 B:G206 4.0 15.9 1.0 O B:HOH322 4.4 17.6 1.0 N1 B:G207 4.5 22.1 1.0 OP2 B:G206 4.5 22.6 1.0 OP2 B:C205 4.6 25.7 1.0 OP2 B:C217 4.6 20.7 1.0 O B:HOH312 4.7 27.9 1.0 C8 B:G206 4.8 17.1 1.0 O6 B:G206 4.8 16.7 1.0 C5 B:G206 4.9 15.5 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure (II) of Nova-1 KH1/KH2 Domain Tandem with 25NT Rna Hairpin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure (II) of Nova-1 KH1/KH2 Domain Tandem with 25NT Rna Hairpin within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg306 b:4.9 occ:0.50 O6 B:G206 2.2 16.7 1.0 O B:HOH332 2.2 15.4 1.0 O B:HOH333 2.3 16.6 1.0 O B:HOH323 2.3 18.3 1.0 C6 B:G206 3.1 17.0 1.0 N1 B:G206 3.2 15.2 1.0 K B:K301 3.7 19.1 0.5 OP2 B:A219 3.8 20.4 1.0 OP2 B:C218 3.9 22.1 1.0 N4 B:C205 4.1 21.5 1.0 O B:HOH322 4.4 17.6 1.0 N1 B:G207 4.4 22.1 1.0 C5 B:G206 4.4 15.5 1.0 O B:HOH304 4.5 25.5 1.0 O B:HOH331 4.5 17.1 1.0 C2 B:G206 4.6 16.0 1.0 N2 B:G207 4.6 21.3 1.0 P B:C218 4.7 24.4 1.0 OP1 B:C218 4.8 23.5 1.0 C2 B:G207 4.9 23.1 1.0 O5' B:C218 5.0 23.3 1.0

M.Teplova, L.Malinina, J.C.Darnell, J.Song, M.Lu, R.Abagyan, K.Musunuru, A.Teplov, S.K.Burley, R.B.Darnell, D.J.Patel. Protein-Rna and Protein-Protein Recognition By Dual KH1/2 Domains of the Neuronal Splicing Factor Nova-1. Structure V. 19 930 2011.
ISSN: ISSN 0969-2126
PubMed: 21742260
DOI: 10.1016/J.STR.2011.05.002