Magnesium in PDB 2bq1: Ribonucleotide Reductase Class 1B Holocomplex R1E,R2F From Salmonella Typhimurium

All present enzymatic activity of Ribonucleotide Reductase Class 1B Holocomplex R1E,R2F From Salmonella Typhimurium:
1.17.4.1;

The structure of Ribonucleotide Reductase Class 1B Holocomplex R1E,R2F From Salmonella Typhimurium, PDB code: 2bq1 was solved by M.Uppsten, M.Farnegardh, V.Domkin, U.Uhlin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	182.57 / 4.0
Space group	P 41 3 2
Cell size a, b, c (Å), α, β, γ (°)	270.372, 270.372, 270.372, 90.00, 90.00, 90.00
R / Rfree (%)	26.2 / 31

The structure of Ribonucleotide Reductase Class 1B Holocomplex R1E,R2F From Salmonella Typhimurium also contains other interesting chemical elements:

Iron

(Fe)

4 atoms

The binding sites of Magnesium atom in the Ribonucleotide Reductase Class 1B Holocomplex R1E,R2F From Salmonella Typhimurium (pdb code 2bq1). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Ribonucleotide Reductase Class 1B Holocomplex R1E,R2F From Salmonella Typhimurium, PDB code: 2bq1:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Ribonucleotide Reductase Class 1B Holocomplex R1E,R2F From Salmonella Typhimurium


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Ribonucleotide Reductase Class 1B Holocomplex R1E,R2F From Salmonella Typhimurium within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg1701 b:12.0 occ:1.00 O3G E:DGT1700 2.0 40.1 1.0 O2A E:DGT1700 2.3 37.7 1.0 O1B E:DGT1700 2.7 37.9 1.0 PG E:DGT1700 3.2 40.5 1.0 PA E:DGT1700 3.3 37.4 1.0 O3A E:DGT1700 3.3 37.7 1.0 O1G E:DGT1700 3.4 41.0 1.0 PB E:DGT1700 3.5 38.3 1.0 C5' E:DGT1700 3.9 35.9 1.0 O3B E:DGT1700 3.9 39.3 1.0 O E:ASP185 4.0 46.3 1.0 O5' E:DGT1700 4.0 36.5 1.0 NH2 E:ARG215 4.1 45.8 1.0 CB E:ASN186 4.4 46.2 1.0 O2G E:DGT1700 4.6 40.5 1.0 O1A E:DGT1700 4.7 37.7 1.0 CA E:ASN186 4.8 46.1 1.0

Magnesium binding site 2 out of 2 in the Ribonucleotide Reductase Class 1B Holocomplex R1E,R2F From Salmonella Typhimurium


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Ribonucleotide Reductase Class 1B Holocomplex R1E,R2F From Salmonella Typhimurium within 5.0Å range: probe atom residue distance (Å) B Occ F:Mg1701 b:33.8 occ:1.00 O2A F:DGT1700 1.9 47.8 1.0 O3G F:DGT1700 2.0 51.5 1.0 O1B F:DGT1700 2.2 50.7 1.0 PA F:DGT1700 3.2 47.6 1.0 PB F:DGT1700 3.2 51.0 1.0 O3A F:DGT1700 3.3 48.9 1.0 PG F:DGT1700 3.4 51.5 1.0 O3B F:DGT1700 3.7 50.9 1.0 O F:ASP185 4.1 58.0 1.0 CB F:ASN186 4.1 57.5 1.0 C5' F:DGT1700 4.2 45.2 1.0 O5' F:DGT1700 4.2 46.3 1.0 O1A F:DGT1700 4.3 47.4 1.0 O2G F:DGT1700 4.3 51.6 1.0 O1G F:DGT1700 4.4 51.7 1.0 NH2 F:ARG215 4.5 59.6 1.0 CA F:ASN186 4.6 57.4 1.0 O2B F:DGT1700 4.7 51.3 1.0

M.Uppsten, M.Farnegardh, V.Domkin, U.Uhlin. The First Holocomplex Structure of Ribonucleotide Reductase Gives New Insight Into Its Mechanism of Action J.Mol.Biol. V. 359 365 2006.
ISSN: ISSN 0022-2836
PubMed: 16631785
DOI: 10.1016/J.JMB.2006.03.035