Magnesium in PDB 2c47: Structure of Casein Kinase 1 Gamma 2

The structure of Structure of Casein Kinase 1 Gamma 2, PDB code: 2c47 was solved by G.Bunkoczi, P.Rellos, S.Das, E.Ugochukwu, O.Fedorov, F.Sobott, J.Eswaran, A.Amos, L.Ball, F.Von Delft, A.Bullock, J.Debreczeni, A.Turnbull, M.Sundstrom, J.Weigelt, C.Arrowsmith, A.Edwards, S.Knapp, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	93.959, 97.088, 185.914, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 25.7

The structure of Structure of Casein Kinase 1 Gamma 2 also contains other interesting chemical elements:

Iodine

(I)

4 atoms

The binding sites of Magnesium atom in the Structure of Casein Kinase 1 Gamma 2 (pdb code 2c47). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Casein Kinase 1 Gamma 2, PDB code: 2c47:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of Casein Kinase 1 Gamma 2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Casein Kinase 1 Gamma 2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1301 b:32.2 occ:1.00 O A:HOH2021 2.8 33.2 1.0 O B:HOH2056 3.1 47.4 1.0 N B:LYS261 3.4 55.3 1.0 O A:HOH2023 3.5 48.9 1.0 N A:LYS113 3.6 60.0 1.0 N B:LEU260 3.6 58.7 1.0 CB B:THR259 3.9 57.1 1.0 CB B:LEU260 3.9 59.5 1.0 CA B:LEU260 4.1 60.7 1.0 CE2 A:TYR114 4.1 53.0 1.0 CB B:LYS261 4.1 59.2 1.0 CA A:GLY112 4.1 57.7 1.0 CD2 A:TYR114 4.1 47.6 1.0 CB A:LYS113 4.2 58.2 1.0 C B:LEU260 4.2 59.3 1.0 CG A:LYS113 4.3 53.5 1.0 OG1 B:THR259 4.3 59.8 1.0 CA B:LYS261 4.4 55.6 1.0 C A:GLY112 4.4 59.8 1.0 O A:CSD111 4.4 34.6 1.0 CA A:LYS113 4.5 61.0 1.0 C B:THR259 4.5 58.3 1.0 CA B:THR259 4.7 58.8 1.0 CG2 B:THR259 4.7 54.9 1.0 CG B:LEU260 4.7 61.5 1.0

Magnesium binding site 2 out of 2 in the Structure of Casein Kinase 1 Gamma 2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Casein Kinase 1 Gamma 2 within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg1301 b:33.9 occ:1.00 O C:HOH2028 2.2 52.2 1.0 O C:ARG295 4.2 60.9 1.0 OD1 C:ASP298 4.2 55.1 1.0 O C:ARG296 4.3 60.8 1.0 O C:LEU297 4.4 57.0 1.0 C C:ARG296 4.6 50.6 1.0 NH1 C:ARG232 4.6 52.0 1.0 CA C:ARG296 4.7 49.0 1.0 ND2 C:ASN222 4.8 55.2 1.0

G.Bunkoczi, P.Rellos, S.Das, E.Ugochukwu, O.Fedorov, F.Sobott, J.Eswaran, A.Amos, L.Ball, F.Von Delft, A.Bullock, J.Debreczeni, A.Turnbull, M.Sundstrom, J.Weigelt, C.Arrowsmith, A.Edwards, S.Knapp. The Structure of Casein Kinase 1 Gamma 2 To Be Published.