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Magnesium in PDB 2cng: Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B
Enzymatic activity of Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B
All present enzymatic activity of Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B:
3.1.3.48;
3.1.3.48;
Protein crystallography data
The structure of Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B, PDB code: 2cng
was solved by
P.J.Ala,
L.Gonneville,
M.Hillman,
M.Becker-Pasha,
E.W.Yue,
B.Douty,
B.Wayland,
P.Polam,
M.L.Crawley,
E.Mclaughlin,
R.B.Sparks,
B.Glass,
A.Takvorian,
A.P.Combs,
T.C.Burn,
G.F.Hollis,
R.Wynn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 7.00 / 1.90 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 74.520, 76.180, 88.560, 90.00, 90.00, 90.00 |
| R / Rfree (%) | n/a / n/a |
Other elements in 2cng:
The structure of Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B also contains other interesting chemical elements:
| Fluorine | (F) | 6 atoms |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B
(pdb code 2cng). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B, PDB code: 2cng:
In total only one binding site of Magnesium was determined in the Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B, PDB code: 2cng:
Magnesium binding site 1 out of 1 in 2cng
Go back to
Magnesium Binding Sites List in 2cng
Magnesium binding site 1 out
of 1 in the Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B within 5.0Å range:
|
Reference:
P.J.Ala,
L.Gonneville,
M.Hillman,
M.Becker-Pasha,
E.W.Yue,
B.Douty,
B.Wayland,
P.Polam,
M.L.Crawley,
E.Mclaughlin,
R.B.Sparks,
B.Glass,
A.Takvorian,
A.P.Combs,
T.C.Burn,
G.F.Hollis,
R.Wynn.
Structural Insights Into the Design of Nonpeptidic Isothiazolidinone-Containing Inhibitors of Protein- Tyrosine Phosphatase 1B. J.Biol.Chem. V. 281 38013 2006.
ISSN: ISSN 0021-9258
PubMed: 17028182
DOI: 10.1074/JBC.M607913200
Page generated: Mon Dec 14 07:19:26 2020
ISSN: ISSN 0021-9258
PubMed: 17028182
DOI: 10.1074/JBC.M607913200
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