Magnesium in PDB 2cv2: Glutamyl-Trna Synthetase From Thermus Thermophilus in Complex with Trna(Glu) and An Enzyme Inhibitor, Glu-Ams

Enzymatic activity of Glutamyl-Trna Synthetase From Thermus Thermophilus in Complex with Trna(Glu) and An Enzyme Inhibitor, Glu-Ams

All present enzymatic activity of Glutamyl-Trna Synthetase From Thermus Thermophilus in Complex with Trna(Glu) and An Enzyme Inhibitor, Glu-Ams:
6.1.1.17;

Protein crystallography data

The structure of Glutamyl-Trna Synthetase From Thermus Thermophilus in Complex with Trna(Glu) and An Enzyme Inhibitor, Glu-Ams, PDB code: 2cv2 was solved by S.Sekine, S.Yokoyama, Riken Structural Genomics/Proteomicsinitiative (Rsgi), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	46.34 / 2.69
*Space group*	C 2 2 2₁
*Cell size a, b, c (Å), α, β, γ (°)*	110.317, 219.822, 135.831, 90.00, 90.00, 90.00
*R / R_free (%)*	20 / 26

Other elements in 2cv2:

The structure of Glutamyl-Trna Synthetase From Thermus Thermophilus in Complex with Trna(Glu) and An Enzyme Inhibitor, Glu-Ams also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Glutamyl-Trna Synthetase From Thermus Thermophilus in Complex with Trna(Glu) and An Enzyme Inhibitor, Glu-Ams (pdb code 2cv2). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Glutamyl-Trna Synthetase From Thermus Thermophilus in Complex with Trna(Glu) and An Enzyme Inhibitor, Glu-Ams, PDB code: 2cv2:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 2cv2

Go back to

Magnesium Binding Sites List in 2cv2

Magnesium binding site 1 out of 2 in the Glutamyl-Trna Synthetase From Thermus Thermophilus in Complex with Trna(Glu) and An Enzyme Inhibitor, Glu-Ams

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Glutamyl-Trna Synthetase From Thermus Thermophilus in Complex with Trna(Glu) and An Enzyme Inhibitor, Glu-Ams within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
C:Mg902 b:36.5 occ:1.00	O	C:HOH1340	2.8	37.3	1.0
	N7	C:A546	3.6	30.7	1.0
	OP2	C:A546	3.8	40.9	1.0
	N7	C:A545	3.9	31.8	1.0
	O2	C:C509	3.9	34.3	1.0
	C8	C:A545	4.2	34.8	1.0
	C8	C:A546	4.3	31.4	1.0
	O	C:HOH1249	4.4	38.9	1.0
	N3	C:C509	4.4	31.0	1.0
	OP2	C:G522	4.4	29.7	1.0
	C5	C:A545	4.5	26.9	1.0
	C5	C:A546	4.5	25.0	1.0
	C2	C:C509	4.6	30.8	1.0
	N6	C:A546	4.7	22.5	1.0
	O	C:HOH1133	4.9	39.4	1.0
	N9	C:A545	5.0	30.3	1.0

Magnesium binding site 2 out of 2 in 2cv2

Go back to

Magnesium Binding Sites List in 2cv2

Magnesium binding site 2 out of 2 in the Glutamyl-Trna Synthetase From Thermus Thermophilus in Complex with Trna(Glu) and An Enzyme Inhibitor, Glu-Ams

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Glutamyl-Trna Synthetase From Thermus Thermophilus in Complex with Trna(Glu) and An Enzyme Inhibitor, Glu-Ams within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
D:Mg901 b:33.8 occ:1.00	N7	D:A546	3.7	29.4	1.0
	OP2	D:G522	4.0	32.6	1.0
	O2	D:C509	4.1	33.6	1.0
	N7	D:A545	4.2	33.5	1.0
	OP2	D:A546	4.3	27.1	1.0
	N3	D:C509	4.4	27.6	1.0
	C8	D:A546	4.4	29.3	1.0
	O	D:HOH1097	4.5	18.8	1.0
	C8	D:A545	4.6	32.9	1.0
	C5	D:A546	4.6	26.7	1.0
	C2	D:C509	4.7	29.0	1.0
	N6	D:A546	4.8	28.3	1.0
	C5	D:A545	4.9	30.2	1.0

Reference:

S.Sekine, M.Shichiri, S.Bernier, R.Chenevert, J.Lapointe, S.Yokoyama. Structural Bases of Transfer Rna-Dependent Amino Acid Recognition and Activation By Glutamyl-Trna Synthetase Structure V. 14 1791 2006.
ISSN: ISSN 0969-2126
PubMed: 17161369
DOI: 10.1016/J.STR.2006.10.005

Page generated: Tue Aug 13 22:21:09 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy