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Atomistry » Magnesium » PDB 2f6y-2fl2 » 2f8z | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 2f6y-2fl2 » 2f8z » |
Magnesium in PDB 2f8z: Crystal Structure of Human Fpps in Complex with Zoledronate and Isopentenyl DiphosphateEnzymatic activity of Crystal Structure of Human Fpps in Complex with Zoledronate and Isopentenyl Diphosphate
All present enzymatic activity of Crystal Structure of Human Fpps in Complex with Zoledronate and Isopentenyl Diphosphate:
2.5.1.1; 2.5.1.10; Protein crystallography data
The structure of Crystal Structure of Human Fpps in Complex with Zoledronate and Isopentenyl Diphosphate, PDB code: 2f8z
was solved by
J.-M.Rondeau,
F.Bitsch,
E.Bourgier,
M.Geiser,
R.Hemmig,
M.Kroemer,
S.Lehmann,
P.Ramage,
S.Rieffel,
A.Strauss,
J.R.Green,
W.Jahnke,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Human Fpps in Complex with Zoledronate and Isopentenyl Diphosphate
(pdb code 2f8z). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Crystal Structure of Human Fpps in Complex with Zoledronate and Isopentenyl Diphosphate, PDB code: 2f8z: Jump to Magnesium binding site number: 1; 2; 3; Magnesium binding site 1 out of 3 in 2f8zGo back to![]() ![]()
Magnesium binding site 1 out
of 3 in the Crystal Structure of Human Fpps in Complex with Zoledronate and Isopentenyl Diphosphate
![]() Mono view ![]() Stereo pair view
Magnesium binding site 2 out of 3 in 2f8zGo back to![]() ![]()
Magnesium binding site 2 out
of 3 in the Crystal Structure of Human Fpps in Complex with Zoledronate and Isopentenyl Diphosphate
![]() Mono view ![]() Stereo pair view
Magnesium binding site 3 out of 3 in 2f8zGo back to![]() ![]()
Magnesium binding site 3 out
of 3 in the Crystal Structure of Human Fpps in Complex with Zoledronate and Isopentenyl Diphosphate
![]() Mono view ![]() Stereo pair view
Reference:
J.M.Rondeau,
F.Bitsch,
E.Bourgier,
M.Geiser,
R.Hemmig,
M.Kroemer,
S.Lehmann,
P.Ramage,
S.Rieffel,
A.Strauss,
J.R.Green,
W.Jahnke.
Structural Basis For the Exceptional in Vivo Efficacy of Bisphosphonate Drugs. Chemmedchem V. 1 267 2006.
Page generated: Tue Aug 13 23:04:54 2024
ISSN: ISSN 1860-7179 PubMed: 16892359 DOI: 10.1002/CMDC.200500059 |
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