Magnesium in PDB 2hhv: T:O6-Methyl-Guanine in the Polymerase-2 Basepair Position

All present enzymatic activity of T:O6-Methyl-Guanine in the Polymerase-2 Basepair Position:
2.7.7.7;

The structure of T:O6-Methyl-Guanine in the Polymerase-2 Basepair Position, PDB code: 2hhv was solved by J.J.Warren, L.J.Forsberg, L.S.Beese, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.55
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	86.956, 93.357, 106.125, 90.00, 90.00, 90.00
R / Rfree (%)	21.6 / 23.9

The binding sites of Magnesium atom in the T:O6-Methyl-Guanine in the Polymerase-2 Basepair Position (pdb code 2hhv). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the T:O6-Methyl-Guanine in the Polymerase-2 Basepair Position, PDB code: 2hhv:

Magnesium binding site 1 out of 1 in the T:O6-Methyl-Guanine in the Polymerase-2 Basepair Position


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of T:O6-Methyl-Guanine in the Polymerase-2 Basepair Position within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg920 b:30.9 occ:1.00 OD1 A:ASP653 2.8 15.8 1.0 O A:TYR654 2.9 12.2 1.0 O A:HOH2525 3.0 17.1 1.0 OD2 A:ASP830 3.1 15.8 1.0 O A:HOH2934 3.3 29.6 1.0 CG A:ASP653 3.7 14.9 1.0 O A:HOH2512 3.8 13.2 1.0 O A:HOH2860 3.8 25.9 1.0 CG A:ASP830 3.9 15.7 1.0 CB A:ASP653 4.0 13.4 1.0 O A:HOH2845 4.0 27.5 1.0 C A:TYR654 4.1 12.4 1.0 OD1 A:ASP830 4.2 15.0 1.0 O A:HOH3296 4.4 33.2 1.0 O A:HOH2977 4.4 36.9 1.0 O A:HOH2645 4.6 32.5 1.0 N A:TYR654 4.6 12.2 1.0 CA A:SER655 4.7 12.9 1.0 C A:ASP653 4.8 12.4 1.0 OD2 A:ASP653 4.8 15.6 1.0 N A:SER655 4.9 12.4 1.0

J.J.Warren, L.J.Forsberg, L.S.Beese. The Structural Basis For the Mutagenicity of O6-Methyl-Guanine Lesions. Proc.Natl.Acad.Sci.Usa V. 103 19701 2006.
ISSN: ISSN 0027-8424
PubMed: 17179038
DOI: 10.1073/PNAS.0609580103