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Atomistry » Magnesium » PDB 2iec-2ivn » 2iso » |
Magnesium in PDB 2iso: Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene TriphosphateEnzymatic activity of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate
All present enzymatic activity of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate:
2.7.7.7; Protein crystallography data
The structure of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate, PDB code: 2iso
was solved by
C.A.Sucato,
T.G.Upton,
B.A.Kashemirov,
V.Martinek,
Y.Xiang,
W.A.Beard,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2iso:
The structure of Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate
(pdb code 2iso). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate, PDB code: 2iso: Magnesium binding site 1 out of 1 in 2isoGo back to Magnesium Binding Sites List in 2iso
Magnesium binding site 1 out
of 1 in the Ternary Complex of Dna Polymerase Beta with A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma- Difluoromethylene Triphosphate
Mono view Stereo pair view
Reference:
C.A.Sucato,
T.G.Upton,
B.A.Kashemirov,
V.K.Batra,
V.Martinek,
Y.Xiang,
W.A.Beard,
L.C.Pedersen,
S.H.Wilson,
C.E.Mckenna,
J.Florian,
A.Warshel,
M.F.Goodman.
Modifying the Beta,Gamma Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of Dna Polymerase Beta. Biochemistry V. 46 461 2007.
Page generated: Mon Dec 14 07:27:44 2020
ISSN: ISSN 0006-2960 PubMed: 17209556 DOI: 10.1021/BI061517B |
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