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Atomistry » Magnesium » PDB 2iec-2ivn » 2itn » |
Magnesium in PDB 2itn: Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Amp-PnpEnzymatic activity of Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Amp-Pnp
All present enzymatic activity of Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Amp-Pnp:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Amp-Pnp, PDB code: 2itn
was solved by
C.-H.Yun,
T.J.Boggon,
Y.Li,
S.Woo,
H.Greulich,
M.Meyerson,
M.J.Eck,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Amp-Pnp
(pdb code 2itn). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Amp-Pnp, PDB code: 2itn: Magnesium binding site 1 out of 1 in 2itnGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Crystal Structure of Egfr Kinase Domain G719S Mutation in Complex with Amp-Pnp
![]() Mono view ![]() Stereo pair view
Reference:
C.-H.Yun,
T.J.Boggon,
Y.Li,
S.Woo,
H.Greulich,
M.Meyerson,
M.J.Eck.
Structures of Lung Cancer-Derived Egfr Mutants and Inhibitor Complexes: Mechanism of Activation and Insights Into Differential Inhibitor Sensitivity Cancer Cell V. 11 217 2007.
Page generated: Wed Aug 14 00:16:28 2024
ISSN: ISSN 1535-6108 PubMed: 17349580 DOI: 10.1016/J.CCR.2006.12.017 |
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