Magnesium in PDB 2ja8: Cpd Lesion Containing Rna Polymerase II Elongation Complex D

All present enzymatic activity of Cpd Lesion Containing Rna Polymerase II Elongation Complex D:
2.7.7.6;

The structure of Cpd Lesion Containing Rna Polymerase II Elongation Complex D, PDB code: 2ja8 was solved by F.Brueckner, U.Hennecke, T.Carell, P.Cramer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50 / 3.8
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	222.642, 392.845, 282.894, 90.00, 90.00, 90.00
R / Rfree (%)	26.86 / 28.76

The structure of Cpd Lesion Containing Rna Polymerase II Elongation Complex D also contains other interesting chemical elements:

Bromine	(Br)	1 atom
Zinc	(Zn)	8 atoms

The binding sites of Magnesium atom in the Cpd Lesion Containing Rna Polymerase II Elongation Complex D (pdb code 2ja8). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cpd Lesion Containing Rna Polymerase II Elongation Complex D, PDB code: 2ja8:

Magnesium binding site 1 out of 1 in the Cpd Lesion Containing Rna Polymerase II Elongation Complex D


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cpd Lesion Containing Rna Polymerase II Elongation Complex D within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2457 b:35.7 occ:1.00 O3' P:A9 2.3 0.8 1.0 OD2 A:ASP481 2.4 53.6 1.0 OD1 A:ASP485 2.4 46.6 1.0 OD1 A:ASP481 2.4 51.8 1.0 OD1 A:ASP483 2.7 49.9 1.0 CG A:ASP481 2.7 53.1 1.0 OD2 A:ASP483 2.8 49.2 1.0 CG A:ASP483 3.1 47.7 1.0 OD2 A:ASP485 3.1 46.9 1.0 CG A:ASP485 3.1 45.7 1.0 C3' P:A9 3.2 0.1 1.0 O2' P:A9 3.4 0.7 1.0 C4' P:A9 3.7 0.8 1.0 C2' P:A9 3.8 0.1 1.0 CB A:ASP481 4.3 53.1 1.0 C5' P:A9 4.4 0.8 1.0 NH2 A:ARG446 4.4 68.8 1.0 CB A:ASP483 4.6 44.9 1.0 CB A:ASP485 4.6 43.0 1.0 O4' P:A9 4.9 0.2 1.0 N A:ASP481 5.0 52.9 1.0 O5' P:A9 5.0 0.7 1.0

F.Brueckner, U.Hennecke, T.Carell, P.Cramer. Cpd Damage Recognition By Transcribing Rna Polymerase II. Science V. 315 859 2007.
ISSN: ISSN 0036-8075
PubMed: 17290000
DOI: 10.1126/SCIENCE.1135400