Magnesium in PDB 2jc9: Crystal Structure of Human Cytosolic 5'-Nucleotidase II in Complex with Adenosine

All present enzymatic activity of Crystal Structure of Human Cytosolic 5'-Nucleotidase II in Complex with Adenosine:
3.1.3.5;

The structure of Crystal Structure of Human Cytosolic 5'-Nucleotidase II in Complex with Adenosine, PDB code: 2jc9 was solved by K.Wallden, P.Stenmark, C.Arrowsmith, H.Berglund, R.Busam, R.Collins, A.Edwards, M.Ehn, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, B.M.Hallberg, S.L.Holmberg, M.Hogbom, T.Karlberg, T.Kotenyova, A.Magnusdottir, P.Nilsson-Ehle, T.Nyman, D.Ogg, C.Persson, J.Sagemark, M.Sundstrom, J.Uppenberg, A.G.Thorsell, S.Van Den Berg, P.Loppnau, J.Weigelt, M.Welin, P.Nordlund, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	74.33 / 1.5
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	91.273, 127.983, 130.601, 90.00, 90.00, 90.00
R / Rfree (%)	16 / 18.6

The binding sites of Magnesium atom in the Crystal Structure of Human Cytosolic 5'-Nucleotidase II in Complex with Adenosine (pdb code 2jc9). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Cytosolic 5'-Nucleotidase II in Complex with Adenosine, PDB code: 2jc9:

Magnesium binding site 1 out of 1 in the Crystal Structure of Human Cytosolic 5'-Nucleotidase II in Complex with Adenosine


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Cytosolic 5'-Nucleotidase II in Complex with Adenosine within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1491 b:11.3 occ:1.00 OD2 A:ASP52 2.0 11.6 1.0 O A:HOH2410 2.0 11.7 1.0 OD1 A:ASP351 2.1 10.1 1.0 O A:HOH2488 2.1 12.4 1.0 O A:ASP54 2.1 10.2 1.0 O A:HOH2487 2.1 10.7 1.0 CG A:ASP52 3.0 11.0 1.0 CG A:ASP351 3.1 10.3 1.0 C A:ASP54 3.3 9.6 1.0 OD2 A:ASP351 3.4 11.0 1.0 OD1 A:ASP52 3.5 11.9 1.0 CA A:ASP54 4.0 10.5 1.0 O4 A:SO41493 4.1 17.1 1.0 N A:ASP54 4.1 10.3 1.0 OG1 A:THR56 4.1 10.6 1.0 O1 A:SO41493 4.1 19.1 1.0 O2 A:SO41493 4.2 20.0 1.0 OD2 A:ASP356 4.2 9.8 1.0 CB A:ASP54 4.3 11.7 1.0 N A:TYR55 4.3 9.7 1.0 CB A:ASP52 4.3 10.5 1.0 CB A:ASP351 4.4 10.7 1.0 S A:SO41493 4.4 17.2 1.0 O A:HOH2291 4.5 15.1 1.0 CB A:TYR55 4.5 9.3 1.0 O A:HOH2072 4.5 12.1 1.0 N A:ASP351 4.6 9.6 1.0 CA A:TYR55 4.7 9.5 1.0 C A:TYR55 4.7 9.6 1.0 C A:MET53 4.7 10.9 1.0 N A:THR56 4.8 9.7 1.0 N A:HIS352 5.0 10.1 1.0 CA A:ASP351 5.0 10.0 1.0

K.Wallden, P.Stenmark, T.Nyman, S.Flodin, S.Graslund, P.Loppnau, V.Bianchi, P.Nordlund. Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition J.Biol.Chem. V. 282 17828 2007.
ISSN: ISSN 0021-9258
PubMed: 17405878
DOI: 10.1074/JBC.M700917200