Magnesium in PDB 2o8d: Human Mutsalpha (MSH2/MSH6) Bound to Adp and A G Du Mispair

The structure of Human Mutsalpha (MSH2/MSH6) Bound to Adp and A G Du Mispair, PDB code: 2o8d was solved by J.J.Warren, T.J.Pohlhaus, A.Changela, P.L.Modrich, L.S.Beese, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 3.00
Space group	P 43 3 2
Cell size a, b, c (Å), α, β, γ (°)	260.379, 260.379, 260.379, 90.00, 90.00, 90.00
R / Rfree (%)	23.9 / 27.8

The binding sites of Magnesium atom in the Human Mutsalpha (MSH2/MSH6) Bound to Adp and A G Du Mispair (pdb code 2o8d). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Human Mutsalpha (MSH2/MSH6) Bound to Adp and A G Du Mispair, PDB code: 2o8d:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Human Mutsalpha (MSH2/MSH6) Bound to Adp and A G Du Mispair


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Mutsalpha (MSH2/MSH6) Bound to Adp and A G Du Mispair within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg935 b:92.4 occ:1.00 OG A:SER676 2.1 90.3 1.0 O1B A:ADP936 2.2 90.9 1.0 CB A:SER676 3.4 90.6 1.0 PB A:ADP936 3.4 91.4 1.0 OD1 A:ASP748 3.8 93.2 1.0 O3B A:ADP936 4.0 91.0 1.0 OD2 A:ASP748 4.0 93.6 1.0 O2B A:ADP936 4.0 90.1 1.0 CG A:ASP748 4.3 93.3 1.0 CA A:SER676 4.5 90.7 1.0 N A:SER676 4.5 90.9 1.0 O3A A:ADP936 4.7 91.0 1.0 OE1 A:GLU749 4.7 92.7 1.0 O2A A:ADP936 4.7 90.5 1.0

Magnesium binding site 2 out of 2 in the Human Mutsalpha (MSH2/MSH6) Bound to Adp and A G Du Mispair


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human Mutsalpha (MSH2/MSH6) Bound to Adp and A G Du Mispair within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg102 b:83.2 occ:1.00 OG B:SER1141 2.2 91.7 1.0 O3B B:ADP202 2.6 0.2 1.0 OD2 B:ASP1213 3.2 92.6 1.0 OD1 B:ASP1213 3.4 92.2 1.0 CB B:SER1141 3.6 91.7 1.0 CG B:ASP1213 3.7 92.2 1.0 PB B:ADP202 3.8 0.2 1.0 N B:SER1141 3.9 92.0 1.0 OE2 B:GLU1214 4.1 94.3 1.0 O2B B:ADP202 4.1 0.0 1.0 CA B:SER1141 4.2 91.7 1.0 CE B:LYS1140 4.3 91.7 1.0 CD B:GLU1214 4.4 93.8 1.0 CB B:LYS1140 4.4 92.2 1.0 O1B B:ADP202 4.5 0.1 1.0 NZ B:LYS1140 4.7 91.7 1.0 OE1 B:GLU1214 4.8 94.1 1.0 C B:LYS1140 4.8 92.2 1.0 OD1 B:ASN1136 4.9 94.0 1.0 CG B:GLU1214 5.0 93.7 1.0 O2A B:ADP202 5.0 0.9 1.0

J.J.Warren, T.J.Pohlhaus, A.Changela, R.R.Iyer, P.L.Modrich, L.S.Beese. Structure of the Human Mutsalpha Dna Lesion Recognition Complex. Mol.Cell V. 26 579 2007.
ISSN: ISSN 1097-2765
PubMed: 17531815
DOI: 10.1016/J.MOLCEL.2007.04.018