Magnesium in PDB 2oi2: Streptococcus Pneumoniae Mevalonate Kinase in Complex with Diphosphomevalonate

All present enzymatic activity of Streptococcus Pneumoniae Mevalonate Kinase in Complex with Diphosphomevalonate:
2.7.1.36;

The structure of Streptococcus Pneumoniae Mevalonate Kinase in Complex with Diphosphomevalonate, PDB code: 2oi2 was solved by J.L.Andreassi, P.W.Bilder, M.W.Vetting, S.L.Roderick, T.S.Leyh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.89 / 2.50
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	101.597, 101.597, 83.280, 90.00, 90.00, 120.00
R / Rfree (%)	21.1 / 27

The binding sites of Magnesium atom in the Streptococcus Pneumoniae Mevalonate Kinase in Complex with Diphosphomevalonate (pdb code 2oi2). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Streptococcus Pneumoniae Mevalonate Kinase in Complex with Diphosphomevalonate, PDB code: 2oi2:

Magnesium binding site 1 out of 1 in the Streptococcus Pneumoniae Mevalonate Kinase in Complex with Diphosphomevalonate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Streptococcus Pneumoniae Mevalonate Kinase in Complex with Diphosphomevalonate within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg400 b:40.2 occ:1.00 O1A A:DP6300 1.9 37.9 1.0 OG A:SER92 2.1 38.9 1.0 OD2 A:ASP135 2.3 40.7 1.0 O A:HOH458 2.3 35.5 1.0 O1B A:DP6300 2.3 38.9 1.0 PA A:DP6300 3.1 38.6 1.0 PB A:DP6300 3.2 36.4 1.0 CG A:ASP135 3.2 40.2 1.0 O6 A:DP6300 3.3 37.0 1.0 CB A:SER92 3.4 39.3 1.0 CB A:ASP135 3.7 38.6 1.0 O2B A:DP6300 3.7 37.9 1.0 N A:SER92 4.0 42.8 1.0 O2A A:DP6300 4.1 35.3 1.0 O5 A:DP6300 4.1 38.1 1.0 OE1 A:GLU124 4.2 46.0 1.0 C5 A:DP6300 4.2 38.6 1.0 CA A:SER92 4.3 40.4 1.0 OD1 A:ASP135 4.3 41.4 1.0 OE2 A:GLU124 4.4 47.1 1.0 N A:ALA93 4.5 41.1 1.0 CE A:MET129 4.6 40.8 1.0 O3B A:DP6300 4.6 36.0 1.0 CD A:GLU124 4.7 45.9 1.0 O1 A:DP6300 4.8 47.9 1.0 CB A:SER91 4.8 43.6 1.0 NZ A:LYS13 4.9 41.6 1.0 C A:SER92 4.9 41.1 1.0 OG A:SER91 4.9 43.3 1.0 O A:HOH409 5.0 36.9 1.0

J.L.Andreassi, P.W.Bilder, M.W.Vetting, S.L.Roderick, T.S.Leyh. Crystal Structure of the Streptococcus Pneumoniae Mevalonate Kinase in Complex with Diphosphomevalonate. Protein Sci. V. 16 983 2007.
ISSN: ISSN 0961-8368
PubMed: 17400916
DOI: 10.1110/PS.072755707