Magnesium in PDB 2ozo: Autoinhibited Intact Human Zap-70

All present enzymatic activity of Autoinhibited Intact Human Zap-70:
2.7.10.2;

The structure of Autoinhibited Intact Human Zap-70, PDB code: 2ozo was solved by S.Deindl, T.A.Kadlecek, T.Brdicka, X.Cao, A.Weiss, J.Kuriyan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	500.00 / 2.60
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	48.297, 52.929, 69.331, 105.91, 92.94, 103.72
R / Rfree (%)	22 / 29

The binding sites of Magnesium atom in the Autoinhibited Intact Human Zap-70 (pdb code 2ozo). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Autoinhibited Intact Human Zap-70, PDB code: 2ozo:

Magnesium binding site 1 out of 1 in the Autoinhibited Intact Human Zap-70


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Autoinhibited Intact Human Zap-70 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg614 b:28.8 occ:1.00 OD1 A:ASN466 2.4 32.6 1.0 OD1 A:ASP479 2.4 51.5 1.0 O2B A:ANP615 2.5 42.5 1.0 O2A A:ANP615 2.5 42.4 1.0 O3A A:ANP615 2.8 41.4 1.0 O2G A:ANP615 2.8 48.9 1.0 PB A:ANP615 3.1 41.0 1.0 PA A:ANP615 3.2 42.0 1.0 CG A:ASP479 3.4 49.4 1.0 CG A:ASN466 3.6 32.1 1.0 N3B A:ANP615 3.8 46.6 1.0 PG A:ANP615 3.9 52.5 1.0 C5' A:ANP615 3.9 40.0 1.0 O5' A:ANP615 4.0 41.4 1.0 O A:ARG465 4.0 24.9 1.0 NZ A:LYS369 4.1 40.1 1.0 OG A:SER478 4.1 22.4 1.0 OD2 A:ASP479 4.2 50.5 1.0 CB A:ASP479 4.2 44.5 1.0 O1A A:ANP615 4.4 42.5 1.0 CA A:ASN466 4.4 27.9 1.0 O1B A:ANP615 4.4 43.1 1.0 ND2 A:ASN466 4.5 34.7 1.0 CB A:ASN466 4.6 29.7 1.0 C A:ARG465 4.7 26.5 1.0 O3G A:ANP615 4.8 50.8 1.0 O A:HOH655 4.8 36.6 1.0 O1G A:ANP615 4.9 48.6 1.0 N A:ASN466 4.9 27.1 1.0

S.Deindl, T.A.Kadlecek, T.Brdicka, X.Cao, A.Weiss, J.Kuriyan. Structural Basis For the Inhibition of Tyrosine Kinase Activity of Zap-70. Cell(Cambridge,Mass.) V. 129 735 2007.
ISSN: ISSN 0092-8674
PubMed: 17512407
DOI: 10.1016/J.CELL.2007.03.039