Magnesium in PDB 2qo9: Human EPHA3 Kinase and Juxtamembrane Region, Phosphorylated, Amp-Pnp Bound

All present enzymatic activity of Human EPHA3 Kinase and Juxtamembrane Region, Phosphorylated, Amp-Pnp Bound:
2.7.10.1;

The structure of Human EPHA3 Kinase and Juxtamembrane Region, Phosphorylated, Amp-Pnp Bound, PDB code: 2qo9 was solved by T.Davis, J.R.Walker, E.M.Newman, F.Mackenzie, C.Butler-Cole, J.Weigelt, M.Sundstrom, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, S.Dhe-Paganon, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	18.51 / 1.55
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	53.839, 38.205, 76.474, 90.00, 102.16, 90.00
R / Rfree (%)	18.2 / 21.1

The binding sites of Magnesium atom in the Human EPHA3 Kinase and Juxtamembrane Region, Phosphorylated, Amp-Pnp Bound (pdb code 2qo9). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human EPHA3 Kinase and Juxtamembrane Region, Phosphorylated, Amp-Pnp Bound, PDB code: 2qo9:

Magnesium binding site 1 out of 1 in the Human EPHA3 Kinase and Juxtamembrane Region, Phosphorylated, Amp-Pnp Bound


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human EPHA3 Kinase and Juxtamembrane Region, Phosphorylated, Amp-Pnp Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1 b:61.2 occ:1.00 O3G A:ANP948 2.0 31.6 0.5 O A:HOH1177 2.2 39.9 1.0 O2B A:ANP948 2.5 30.9 0.5 O A:HOH1127 2.5 31.2 1.0 O1A A:ANP948 2.6 27.4 0.5 O A:HOH1183 3.2 32.7 1.0 PG A:ANP948 3.3 30.8 0.5 O A:HOH1195 3.6 43.1 1.0 PB A:ANP948 3.6 30.4 0.5 O1G A:ANP948 3.8 35.8 1.0 N3B A:ANP948 3.8 30.9 0.5 O A:ARG750 3.9 14.5 1.0 PA A:ANP948 3.9 26.7 0.5 OD1 A:ASN751 4.0 16.4 1.0 O3A A:ANP948 4.2 29.6 0.5 O2G A:ANP948 4.4 29.4 0.5 O A:HOH1276 4.5 45.8 1.0 C A:ARG750 4.8 12.9 1.0 O2A A:ANP948 4.8 26.1 0.5 OD2 A:ASP764 4.8 23.5 0.5 CB A:ARG750 4.9 12.8 0.5 CB A:ARG750 4.9 12.6 0.5 CG A:ARG750 4.9 13.7 0.5 O A:HOH1105 4.9 26.7 1.0 O1B A:ANP948 4.9 29.8 0.5 CD A:ARG750 5.0 15.4 0.5 OG A:SER706 5.0 18.4 1.0 O A:HOH1133 5.0 24.7 1.0

T.L.Davis, J.R.Walker, P.Loppnau, C.Butler-Cole, A.Allali-Hassani, S.Dhe-Paganon. Autoregulation By the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EPHA3). Structure V. 16 873 2008.
ISSN: ISSN 0969-2126
PubMed: 18547520
DOI: 10.1016/J.STR.2008.03.008