Atomistry » Magnesium » PDB 2q9y-2qrf » 2qoc
Atomistry »
  Magnesium »
    PDB 2q9y-2qrf »
      2qoc »

Magnesium in PDB 2qoc: Human EPHA3 Kinase Domain, Phosphorylated, Amp-Pnp Bound Structure

Enzymatic activity of Human EPHA3 Kinase Domain, Phosphorylated, Amp-Pnp Bound Structure

All present enzymatic activity of Human EPHA3 Kinase Domain, Phosphorylated, Amp-Pnp Bound Structure:
2.7.10.1;

Protein crystallography data

The structure of Human EPHA3 Kinase Domain, Phosphorylated, Amp-Pnp Bound Structure, PDB code: 2qoc was solved by T.Davis, J.R.Walker, E.M.Newman, F.Mackenzie, C.Butler-Cole, J.Weigelt, M.Sundstrom, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, S.Dhe-Paganon, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.45 / 1.25
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 53.790, 38.337, 76.439, 90.00, 102.07, 90.00
R / Rfree (%) 16.9 / 18.6

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Human EPHA3 Kinase Domain, Phosphorylated, Amp-Pnp Bound Structure (pdb code 2qoc). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Human EPHA3 Kinase Domain, Phosphorylated, Amp-Pnp Bound Structure, PDB code: 2qoc:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 2qoc

Go back to Magnesium Binding Sites List in 2qoc
Magnesium binding site 1 out of 2 in the Human EPHA3 Kinase Domain, Phosphorylated, Amp-Pnp Bound Structure


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human EPHA3 Kinase Domain, Phosphorylated, Amp-Pnp Bound Structure within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1

b:15.2
occ:0.50
O3G A:ANP949 1.1 15.6 0.4
O1A A:ANP949 1.7 14.9 0.6
O A:HOH1372 1.7 34.7 1.0
PA A:ANP949 2.5 14.1 0.6
PG A:ANP949 2.6 9.1 0.4
O3G A:ANP949 2.7 12.1 0.6
O2A A:ANP949 2.7 12.1 0.6
O A:HOH1368 3.2 19.6 1.0
O1B A:ANP949 3.3 11.6 0.5
O2G A:ANP949 3.4 14.0 0.4
O1G A:ANP949 3.6 15.0 0.4
N3B A:ANP949 3.7 9.4 0.5
O5' A:ANP949 3.7 15.3 1.0
O3A A:ANP949 3.7 13.4 0.6
CA A:GLY630 3.9 26.8 1.0
PG A:ANP949 4.1 10.9 0.6
PB A:ANP949 4.2 10.9 0.5
MG A:MG2 4.2 25.9 1.0
O A:ALA629 4.2 26.5 1.0
C5' A:ANP949 4.3 14.9 1.0
N A:GLU631 4.7 27.0 1.0
N3B A:ANP949 4.8 12.6 0.5
O A:HOH1340 4.8 3.5 0.5
O1G A:ANP949 4.8 10.9 0.6
C A:GLY630 4.8 27.0 1.0
N A:GLY630 4.8 26.8 1.0
O A:HOH1344 4.9 29.8 1.0
C A:ALA629 4.9 26.2 1.0

Magnesium binding site 2 out of 2 in 2qoc

Go back to Magnesium Binding Sites List in 2qoc
Magnesium binding site 2 out of 2 in the Human EPHA3 Kinase Domain, Phosphorylated, Amp-Pnp Bound Structure


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human EPHA3 Kinase Domain, Phosphorylated, Amp-Pnp Bound Structure within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg2

b:25.9
occ:1.00
O A:HOH1340 2.0 3.5 0.5
OD1 A:ASN751 2.8 10.5 1.0
O1B A:ANP949 2.8 11.6 0.5
O A:HOH1281 2.9 18.1 1.0
O A:HOH1368 3.0 19.6 1.0
OD2 A:ASP764 3.0 9.8 0.5
O1G A:ANP949 3.0 10.9 0.6
O2A A:ANP949 3.1 12.1 0.6
PG A:ANP949 3.6 10.9 0.6
O3G A:ANP949 3.6 12.1 0.6
CB A:ASP764 3.6 10.4 1.0
CG A:ASP764 3.7 9.2 0.5
O A:ARG750 3.7 7.1 0.5
N3B A:ANP949 3.7 12.6 0.5
O3A A:ANP949 3.9 13.4 0.6
O A:HOH1344 3.9 29.8 1.0
PA A:ANP949 3.9 14.1 0.6
O A:ARG750 3.9 7.7 0.5
CG A:ASN751 4.0 8.9 1.0
O A:HOH1149 4.0 32.1 1.0
O A:HOH991 4.1 13.1 1.0
PB A:ANP949 4.2 10.9 0.5
MG A:MG1 4.2 15.2 0.5
O A:HOH1369 4.2 22.3 1.0
O3G A:ANP949 4.4 15.6 0.4
CA A:ASN751 4.4 7.2 1.0
C A:ARG750 4.7 6.8 0.5
O1A A:ANP949 4.7 14.9 0.6
CB A:ASN751 4.7 6.7 1.0
C A:ARG750 4.7 7.2 0.5
OD1 A:ASP764 4.8 10.2 0.5
CA A:ASP764 4.9 9.9 1.0
ND2 A:ASN751 4.9 10.0 1.0
N A:ASN751 5.0 6.9 1.0
OG A:SER763 5.0 9.5 0.5

Reference:

T.L.Davis, J.R.Walker, P.Loppnau, C.Butler-Cole, A.Allali-Hassani, S.Dhe-Paganon. Autoregulation By the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EPHA3). Structure V. 16 873 2008.
ISSN: ISSN 0969-2126
PubMed: 18547520
DOI: 10.1016/J.STR.2008.03.008
Page generated: Wed Aug 14 02:48:54 2024

Last articles

Na in 6D9B
Na in 6D99
Na in 6D9A
Na in 6D5L
Na in 6D55
Na in 6D5J
Na in 6D5E
Na in 6D56
Na in 6D64
Na in 6D59
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy