Magnesium in PDB 2qrz: CDC42 Bound to Gmp-Pcp: Induced Fit By Effector Is Required

The structure of CDC42 Bound to Gmp-Pcp: Induced Fit By Effector Is Required, PDB code: 2qrz was solved by M.J.Phillips, G.Calero, B.Chan, R.A.Cerione, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.27 / 2.40
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	98.500, 98.500, 102.400, 90.00, 90.00, 90.00
R / Rfree (%)	23.4 / 26.3

The binding sites of Magnesium atom in the CDC42 Bound to Gmp-Pcp: Induced Fit By Effector Is Required (pdb code 2qrz). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the CDC42 Bound to Gmp-Pcp: Induced Fit By Effector Is Required, PDB code: 2qrz:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the CDC42 Bound to Gmp-Pcp: Induced Fit By Effector Is Required


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of CDC42 Bound to Gmp-Pcp: Induced Fit By Effector Is Required within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg190 b:43.2 occ:1.00 OG1 A:THR17 2.0 45.0 1.0 O1G A:GCP3639 2.1 51.1 1.0 O2B A:GCP3639 2.2 47.6 1.0 O A:HOH3710 2.2 42.6 1.0 O A:HOH3642 2.4 47.2 1.0 O A:HOH3641 2.4 43.0 1.0 CB A:THR17 3.1 47.0 1.0 PG A:GCP3639 3.4 53.8 1.0 PB A:GCP3639 3.5 47.7 1.0 OD2 A:ASP57 3.7 45.1 1.0 N A:THR17 3.9 44.9 1.0 C3B A:GCP3639 3.9 52.0 1.0 O3G A:GCP3639 4.0 53.0 1.0 CA A:THR17 4.0 44.8 1.0 CG2 A:THR17 4.2 45.0 1.0 O2A A:GCP3639 4.2 47.2 1.0 OD1 A:ASP57 4.3 43.3 1.0 CG A:ASP57 4.4 46.6 1.0 CE1 A:PHE37 4.4 51.1 1.0 O1B A:GCP3639 4.4 51.8 1.0 O A:HOH3670 4.5 74.4 1.0 O3A A:GCP3639 4.5 49.2 1.0 O1A A:GCP3639 4.6 49.6 1.0 O2G A:GCP3639 4.6 56.4 1.0 PA A:GCP3639 4.6 49.3 1.0 CD1 A:PHE37 4.6 47.2 1.0 O A:THR58 4.8 48.9 1.0 C A:LYS16 5.0 44.5 1.0

Magnesium binding site 2 out of 2 in the CDC42 Bound to Gmp-Pcp: Induced Fit By Effector Is Required


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of CDC42 Bound to Gmp-Pcp: Induced Fit By Effector Is Required within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg190 b:77.0 occ:1.00 OG1 B:THR17 2.3 65.5 1.0 O B:HOH194 2.4 95.2 1.0 O1G B:GCP191 2.4 75.0 1.0 O B:HOH207 2.6 68.3 1.0 O2B B:GCP191 2.7 71.8 1.0 O B:HOH192 2.7 57.2 1.0 CB B:THR17 3.1 64.8 1.0 PG B:GCP191 3.6 76.2 1.0 O2A B:GCP191 3.9 72.2 1.0 CG2 B:THR17 3.9 64.6 1.0 PB B:GCP191 3.9 73.1 1.0 C3B B:GCP191 4.1 73.3 1.0 OD2 B:ASP57 4.2 67.8 1.0 O B:PRO34 4.2 1.0 1.0 O2G B:GCP191 4.3 78.2 1.0 CA B:THR17 4.4 64.3 1.0 N B:THR17 4.5 66.1 1.0 PA B:GCP191 4.7 73.2 1.0 O1A B:GCP191 4.8 73.6 1.0 O3A B:GCP191 4.8 70.8 1.0 O3G B:GCP191 4.9 74.8 1.0 CG B:ASP57 5.0 68.2 1.0

M.J.Phillips, G.Calero, B.Chan, S.Ramachandran, R.A.Cerione. Effector Proteins Exert An Important Influence on the Signaling-Active State of the Small Gtpase CDC42. J.Biol.Chem. V. 283 14153 2008.
ISSN: ISSN 0021-9258
PubMed: 18348980
DOI: 10.1074/JBC.M706271200